ENSG00000136122


Homo sapiens

Features
Gene ID: ENSG00000136122
  
Biological name :BORA
  
Synonyms : BORA / bora, aurora kinase A activator / Q6PGQ7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q21.33
Gene start: 72727749
Gene end: 72756198
  
Corresponding Affymetrix probe sets: 219544_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367046
Ensembl peptide - ENSP00000479349
Ensembl peptide - ENSP00000479266
Ensembl peptide - ENSP00000375082
Ensembl peptide - ENSP00000367045
NCBI entrez gene - 79866     See in Manteia.
OMIM - 610510
RefSeq - XM_006719868
RefSeq - NM_001286746
RefSeq - NM_001286747
RefSeq - NM_024808
RefSeq Peptide - NP_079084
RefSeq Peptide - NP_001273675
RefSeq Peptide - NP_001273676
swissprot - A0A087WV86
swissprot - H3BLY2
swissprot - A0A087WVC9
swissprot - Q6PGQ7
swissprot - B5LMG6
Ensembl - ENSG00000136122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 boraENSDARG00000042688Danio rerio
 BORAENSGALG00000016931Gallus gallus
 BoraENSMUSG00000022070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR023252  Aurora borealis protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007088 regulation of mitotic nuclear division IMP
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0072687 meiotic spindle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000072803 FBXW11 / Q9UKB1 / F-box and WD repeat domain containing 11  / reaction / complex
 ENSG00000134057 CCNB1 / P14635 / cyclin B1  / reaction
 ENSG00000087586 AURKA / O14965 / aurora kinase A  / complex / reaction
 ENSG00000157456 CCNB2 / O95067 / cyclin B2  / reaction
 ENSG00000055130 CUL1 / Q13616 / cullin 1  / reaction / complex
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / reaction
 ENSG00000113558 SKP1 / P63208 / S-phase kinase associated protein 1  / reaction / complex
 ENSG00000166167 BTRC / Q9Y297 / beta-transducin repeat containing E3 ubiquitin protein ligase  / complex / reaction
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction / complex






 

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