ENSG00000114745


Homo sapiens

Features
Gene ID: ENSG00000114745
  
Biological name :GORASP1
  
Synonyms : golgi reassembly stacking protein 1 / GORASP1 / Q9BQQ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p22.2
Gene start: 39096659
Gene end: 39108363
  
Corresponding Affymetrix probe sets: 215749_s_at (Human Genome U133 Plus 2.0 Array)   243677_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392993
Ensembl peptide - ENSP00000395241
Ensembl peptide - ENSP00000419123
Ensembl peptide - ENSP00000411104
Ensembl peptide - ENSP00000405976
Ensembl peptide - ENSP00000403552
Ensembl peptide - ENSP00000403167
Ensembl peptide - ENSP00000395709
Ensembl peptide - ENSP00000313869
Ensembl peptide - ENSP00000392020
NCBI entrez gene - 64689     See in Manteia.
OMIM - 606867
RefSeq - XM_017007052
RefSeq - NM_001278789
RefSeq - NM_001278790
RefSeq - NM_031899
RefSeq - XM_006713301
RefSeq - XM_011534020
RefSeq - XM_011534021
RefSeq - XM_017007050
RefSeq - XM_017007051
RefSeq Peptide - NP_001265719
RefSeq Peptide - NP_001265718
RefSeq Peptide - NP_114105
swissprot - C9J0V5
swissprot - Q9BQQ3
swissprot - B3KPY8
swissprot - A0A024R2U5
swissprot - G3V0G1
swissprot - H7C0J2
swissprot - B4E1H8
swissprot - C9J9V9
swissprot - C9J5S6
Ensembl - ENSG00000114745
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gorasp1aENSDARG00000003068Danio rerio
 GORASP1ENSGALG00000006033Gallus gallus
 Q91X51ENSMUSG00000032513Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H8Y8 / GORASP2 / golgi reassembly stacking protein 2ENSG0000011580640


Protein motifs (from Interpro)
Interpro ID Name
 IPR007583  GRASP55/65
 IPR024958  GRASP55/65 PDZ-like domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006487 protein N-linked glycosylation IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0007030 Golgi organization ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:0050774 negative regulation of dendrite morphogenesis IMP
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108433 GOSR2 / O14653 / golgi SNAP receptor complex member 2  / reaction
 ENSG00000105829 BET1 / O15155 / Bet1 golgi vesicular membrane trafficking protein  / reaction
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / reaction / complex
 ENSG00000138674 O94979 / SEC31A / SEC31 homolog A, COPII coat complex component  / reaction / complex
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000134057 CCNB1 / P14635 / cyclin B1  / reaction
 ENSG00000162236 STX5 / Q13190 / syntaxin 5  / reaction
 ENSG00000141551 CSNK1D / P48730 / casein kinase 1 delta  / reaction
 ENSG00000157456 CCNB2 / O95067 / cyclin B2  / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / reaction / complex
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / reaction / complex
 ENSG00000092108 SCFD1 / Q8WVM8 / sec1 family domain containing 1  / reaction
 ENSG00000157020 SEC13 / P55735 / SEC13 homolog, nuclear pore and COPII coat complex component  / complex / reaction
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000138069 RAB1A / P62820 / RAB1A, member RAS oncogene family  / complex / reaction
 ENSG00000167110 GOLGA2 / Q08379 / golgin A2  / complex
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction / complex
 ENSG00000107651 Q9Y6Y8 / SEC23IP / SEC23 interacting protein  / complex / reaction
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex / reaction






 

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