ENSG00000162236


Homo sapiens

Features
Gene ID: ENSG00000162236
  
Biological name :STX5
  
Synonyms : Q13190 / STX5 / syntaxin 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.3
Gene start: 62806897
Gene end: 62832088
  
Corresponding Affymetrix probe sets: 203330_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414289
Ensembl peptide - ENSP00000432748
Ensembl peptide - ENSP00000436495
Ensembl peptide - ENSP00000435973
Ensembl peptide - ENSP00000434107
Ensembl peptide - ENSP00000294179
Ensembl peptide - ENSP00000367129
Ensembl peptide - ENSP00000378182
NCBI entrez gene - 6811     See in Manteia.
OMIM - 603189
RefSeq - XM_011545224
RefSeq - NM_001244666
RefSeq - NM_001330294
RefSeq - NM_003164
RefSeq - XM_011545223
RefSeq Peptide - NP_003155
RefSeq Peptide - NP_001231595
RefSeq Peptide - NP_001317223
swissprot - H0YEJ8
swissprot - H7C3X5
swissprot - E9PP18
swissprot - E9PNU4
swissprot - Q13190
swissprot - E9PRW9
Ensembl - ENSG00000162236
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx5aENSDARG00000025033Danio rerio
 stx5alENSDARG00000003175Danio rerio
 Stx5aENSMUSG00000010110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR021538  Syntaxin-5, N-terminal, Sly1p-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034498 early endosome to Golgi transport IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IDA
 biological_processGO:0045732 positive regulation of protein catabolic process IMP
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IEA
 biological_processGO:0090166 Golgi disassembly IDA
 biological_processGO:1903358 regulation of Golgi organization IDA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031201 SNARE complex TAS
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0047485 protein N-terminus binding IPI


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-mediated anterograde transport
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106636 YKT6 / O15498 / YKT6 v-SNARE homolog  / complex
 ENSG00000108587 GOSR1 / O95249 / golgi SNAP receptor complex member 1  / complex / reaction
 ENSG00000108433 GOSR2 / O14653 / golgi SNAP receptor complex member 2  / complex
 ENSG00000105829 BET1 / O15155 / Bet1 golgi vesicular membrane trafficking protein  / complex
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / complex / reaction
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex / reaction
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / complex / reaction
 ENSG00000173905 GOLIM4 / O00461 / golgi integral membrane protein 4  / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / reaction
 ENSG00000257923 CUX1 / P39880 / Q13948 / cut like homeobox 1  / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / complex / reaction
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction
 ENSG00000167110 GOLGA2 / Q08379 / golgin A2  / reaction
 ENSG00000066455 GOLGA5 / Q8TBA6 / golgin A5  / reaction
 ENSG00000114745 Q9BQQ3 / GORASP1 / golgi reassembly stacking protein 1  / reaction
 ENSG00000092108 SCFD1 / Q8WVM8 / sec1 family domain containing 1  / complex
 ENSG00000177951 BET1L / Q9NYM9 / Bet1 golgi vesicular membrane trafficking protein like  / complex
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction






 

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