ENSMUSG00000010110


Mus musculus

Features
Gene ID: ENSMUSG00000010110
  
Biological name :Stx5a
  
Synonyms : Q8K1E0 / Stx5a / Syntaxin-5
  
Possible biological names infered from orthology : Q13190 / STX5
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 8741413
Gene end: 8756069
  
Corresponding Affymetrix probe sets: 10461176 (MoGene1.0st)   1448267_at (Mouse Genome 430 2.0 Array)   1449679_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134951
Ensembl peptide - ENSMUSP00000135348
Ensembl peptide - ENSMUSP00000135416
Ensembl peptide - ENSMUSP00000135465
Ensembl peptide - ENSMUSP00000135624
Ensembl peptide - ENSMUSP00000010254
Ensembl peptide - ENSMUSP00000073136
Ensembl peptide - ENSMUSP00000134794
Ensembl peptide - ENSMUSP00000134854
Ensembl peptide - ENSMUSP00000134892
Ensembl peptide - ENSMUSP00000135468
NCBI entrez gene - 56389     See in Manteia.
MGI - MGI:1928483
RefSeq - NM_001167799
RefSeq - NM_019829
RefSeq Peptide - NP_001161271
RefSeq Peptide - NP_062803
swissprot - Q8K1E0
swissprot - H3BJ02
swissprot - H3BJ89
swissprot - H3BJE3
swissprot - H3BKD6
swissprot - H3BKJ7
swissprot - H3BKP0
swissprot - H3BKP3
swissprot - H3BL25
swissprot - I1E4X1
Ensembl - ENSMUSG00000010110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx5aENSDARG00000025033Danio rerio
 stx5alENSDARG00000003175Danio rerio
 STX5ENSG00000162236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR021538  Syntaxin-5, N-terminal, Sly1p-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034498 early endosome to Golgi transport ISO
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISO
 biological_processGO:0045732 positive regulation of protein catabolic process ISO
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IEA
 biological_processGO:0061025 membrane fusion IEA
 biological_processGO:0090166 Golgi disassembly ISO
 biological_processGO:1903358 regulation of Golgi organization ISO
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0031982 vesicle ISO
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0047485 protein N-terminus binding ISO


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-mediated anterograde transport
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002741 Ykt6 / Q9CQW1 / YKT6 v-SNARE homolog (S. cerevisiae) / O15498* / YKT6 v-SNARE homolog*  / complex
 ENSMUSG00000006024 Napa / Q9DB05 / Alpha-soluble NSF attachment protein / P54920* / NSF attachment protein alpha*  / reaction / complex
 ENSMUSG00000034187 Nsf / P46460 / Vesicle-fusing ATPase / P46459* / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / complex / reaction
 ENSMUSG00000010392 Gosr1 / O88630 / golgi SNAP receptor complex member 1 / O95249*  / complex / reaction
 ENSMUSG00000020946 Gosr2 / O35166 / golgi SNAP receptor complex member 2 / O14653* / AC005670.2*  / complex
 ENSMUSG00000020952 Scfd1 / Q8BRF7 / Sec1 family domain-containing protein 1 / Q8WVM8* / sec1 family domain containing 1*  / complex
 ENSMUSG00000039234 Sec24d / Sec24 related gene family, member D (S. cerevisiae) / O94855* / SEC24 homolog D, COPII coat complex component*  / complex / reaction
 ENSMUSG00000027879 O08547 / Sec22b / Vesicle-trafficking protein SEC22b / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / reaction / complex
 ENSMUSG00000025484 Bet1l / O35153 / BET1-like protein / Q9NYM9* / Bet1 golgi vesicular membrane trafficking protein like*  / complex
 ENSMUSG00000032513 Q91X51 / Gorasp1 / golgi reassembly stacking protein 1 / Q9BQQ3*  / reaction
 ENSMUSG00000032757 Bet1 / O35623 / BET1 homolog / O15155* / Bet1 golgi vesicular membrane trafficking protein*  / complex
 ENSMUSG00000029407 Uso1 / Q9Z1Z0 / USO1 vesicle docking factor / O60763* / USO1 vesicle transport factor*  / reaction
 ENSMUSG00000002546 Golga2 / Q921M4 / golgi autoantigen, golgin subfamily a, 2 / A7E2F4* / A8MQT2* / D6RF30* / F8WBI6* / A6NCC3* / A6NDK9* / A6NDN3* / A6NMD2* / H3BSY2* / I6L899* / P0CG33* / P0CJ92* / Q08379* ...  / reaction
 ENSMUSG00000020986 Q01405 / Sec23a / Protein transport protein Sec23A / Q15436* / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSMUSG00000021192 Golga5 / Q9QYE6 / golgi autoantigen, golgin subfamily a, 5 / Q8TBA6* / golgin A5*  / reaction
 ENSMUSG00000034109 Golim4 / Q8BXA1 / golgi integral membrane protein 4 / O00461*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr