ENSG00000167110


Homo sapiens

Features
Gene ID: ENSG00000167110
  
Biological name :GOLGA2
  
Synonyms : GOLGA2 / golgin A2 / Q08379
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 128255829
Gene end: 128275995
  
Corresponding Affymetrix probe sets: 204384_at (Human Genome U133 Plus 2.0 Array)   211059_s_at (Human Genome U133 Plus 2.0 Array)   225672_at (Human Genome U133 Plus 2.0 Array)   35436_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473603
Ensembl peptide - ENSP00000491980
Ensembl peptide - ENSP00000481685
Ensembl peptide - ENSP00000478799
Ensembl peptide - ENSP00000476265
Ensembl peptide - ENSP00000409271
Ensembl peptide - ENSP00000411598
Ensembl peptide - ENSP00000416097
NCBI entrez gene - 2801     See in Manteia.
OMIM - 602580
RefSeq - NM_004486
RefSeq - XM_005251932
RefSeq - XM_005251931
RefSeq - XM_005251930
RefSeq Peptide - NP_004477
swissprot - B7ZC06
swissprot - Q08379
swissprot - R4GND7
swissprot - H0Y7B8
swissprot - A0A087WYC0
swissprot - A0A1W2PQY5
Ensembl - ENSG00000167110
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 golga2ENSDARG00000063197Danio rerio
 ENSGALG00000004881Gallus gallus
 Golga2ENSMUSG00000002546Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NDK9 / GOLGA6C / golgin A6 family member CENSG0000016719536
A6NDN3 / GOLGA6B / golgin A6 family member BENSG0000021518636
Q9NYA3 / GOLGA6A / golgin A6 family member AENSG0000015928936
P0CG33 / GOLGA6D / golgin A6 family member DENSG0000014047835
Q08AF8 / GOLGA8F / golgin A8 family member FENSG0000015368431
GOLGA8G / golgin A8 family member GENSG0000018362931
GOLGA8S / golgin A8 family member SENSG0000026173931
H3BSY2 / GOLGA8M / golgin A8 family member MENSG0000018862629
D6RF30 / GOLGA8K / golgin A8 family member KENSG0000024993129
F8WBI6 / GOLGA8N / golgin A8 family member NENSG0000023265329
A6NMD2 / GOLGA8J / golgin A8 family member JENSG0000017993829
GOLGA8T / golgin A8 family member TENSG0000026124729
I6L899 / GOLGA8R / golgin A8 family member RENSG0000018639929
GOLGA8Q / golgin A8 family member QENSG0000017811529
A6NCC3 / GOLGA8O / golgin A8 family member OENSG0000020612729
P0CJ92 / GOLGA8H / golgin A8 family member HENSG0000026179428
A8MQT2 / GOLGA8B / golgin A8 family member BENSG0000021525226
A7E2F4 / GOLGA8A / golgin A8 family member AENSG0000017526526
Q8N9W4 / GOLGA6L2 / golgin A6 family-like 2ENSG0000017445021
GOLGA6L7 / golgin A6 family like 7ENSG0000026164920


Protein motifs (from Interpro)
Interpro ID Name
 IPR024858  Golgin subfamily A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0007020 microtubule nucleation IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle IMP
 biological_processGO:0008356 asymmetric cell division ISS
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:0051225 spindle assembly IMP
 biological_processGO:0051289 protein homotetramerization ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060050 positive regulation of protein glycosylation IMP
 biological_processGO:0090161 Golgi ribbon formation IMP
 biological_processGO:0090166 Golgi disassembly ISS
 biological_processGO:0090306 spindle assembly involved in meiosis ISS
 biological_processGO:0090307 mitotic spindle assembly IDA
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity TAS
 cellular_componentGO:0000137 Golgi cis cisterna IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0000922 spindle pole ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030134 COPII-coated ER to Golgi transport vesicle IMP
 cellular_componentGO:0032580 Golgi cisterna membrane ISS
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane TAS
 cellular_componentGO:0072686 mitotic spindle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019905 syntaxin binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0061676 importin-alpha family protein binding ISS


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimers disease models


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108433 GOSR2 / O14653 / golgi SNAP receptor complex member 2  / reaction
 ENSG00000105829 BET1 / O15155 / Bet1 golgi vesicular membrane trafficking protein  / reaction
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / reaction / complex
 ENSG00000138674 O94979 / SEC31A / SEC31 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / reaction / complex
 ENSG00000134057 CCNB1 / P14635 / cyclin B1  / reaction
 ENSG00000162236 STX5 / Q13190 / syntaxin 5  / reaction
 ENSG00000141551 CSNK1D / P48730 / casein kinase 1 delta  / reaction
 ENSG00000157456 CCNB2 / O95067 / cyclin B2  / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / reaction / complex
 ENSG00000164885 CDK5 / Q00535 / cyclin dependent kinase 5  / reaction
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / complex / reaction
 ENSG00000092108 SCFD1 / Q8WVM8 / sec1 family domain containing 1  / reaction
 ENSG00000157020 SEC13 / P55735 / SEC13 homolog, nuclear pore and COPII coat complex component  / complex / reaction
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / reaction / complex
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000114745 Q9BQQ3 / GORASP1 / golgi reassembly stacking protein 1  / complex
 ENSG00000107651 Q9Y6Y8 / SEC23IP / SEC23 interacting protein  / reaction / complex
 ENSG00000138069 RAB1A / P62820 / RAB1A, member RAS oncogene family  / complex / reaction
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction / complex
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex / reaction






 

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