ENSG00000112576


Homo sapiens

Features
Gene ID: ENSG00000112576
  
Biological name :CCND3
  
Synonyms : CCND3 / cyclin D3 / P30281
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 41934933
Gene end: 42050357
  
Corresponding Affymetrix probe sets: 1562028_at (Human Genome U133 Plus 2.0 Array)   201700_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421511
Ensembl peptide - ENSP00000423242
Ensembl peptide - ENSP00000484424
Ensembl peptide - ENSP00000426212
Ensembl peptide - ENSP00000425986
Ensembl peptide - ENSP00000425830
Ensembl peptide - ENSP00000425334
Ensembl peptide - ENSP00000362078
Ensembl peptide - ENSP00000362079
Ensembl peptide - ENSP00000362082
Ensembl peptide - ENSP00000397545
Ensembl peptide - ENSP00000401595
Ensembl peptide - ENSP00000420991
NCBI entrez gene - 896     See in Manteia.
OMIM - 123834
RefSeq - XM_011514972
RefSeq - NM_001136017
RefSeq - NM_001136125
RefSeq - NM_001136126
RefSeq - NM_001287427
RefSeq - NM_001287434
RefSeq - NM_001760
RefSeq - XM_011514971
RefSeq Peptide - NP_001751
RefSeq Peptide - NP_001129489
RefSeq Peptide - NP_001129597
RefSeq Peptide - NP_001129598
RefSeq Peptide - NP_001274356
RefSeq Peptide - NP_001274363
swissprot - H0Y8M4
swissprot - D6RI00
swissprot - D6RDL3
swissprot - P30281
swissprot - Q5T8J1
swissprot - D6RIX2
swissprot - D6RDF8
swissprot - A0A1D5RMS0
Ensembl - ENSG00000112576
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccnd3ENSDARG00000027391Danio rerio
 CCND3ENSGALG00000003485Gallus gallus
 Ccnd3ENSMUSG00000034165Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCND2 / P30279 / cyclin D2ENSG0000011897162
CCND1 / P24385 / cyclin D1ENSG0000011009252
CCNE2 / O96020 / cyclin E2ENSG0000017530523
CCNE1 / P24864 / cyclin E1ENSG0000010517323
CCNA1 / P78396 / cyclin A1ENSG0000013310123
CCNA2 / P20248 / cyclin A2ENSG0000014538622
CCNB2 / O95067 / cyclin B2ENSG0000015745621
CCNO / P22674 / cyclin OENSG0000015266921
CCNB1 / P14635 / cyclin B1ENSG0000013405720
CCNB3 / Q8WWL7 / cyclin B3ENSG0000014708218


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR015451  Cyclin D
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
Transcriptional regulation of white adipocyte differentiation
MAPK6/MAPK4 signaling
Cyclin D associated events in G1
Regulation of RUNX1 Expression and Activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069956 MAPK6 / Q16659 / mitogen-activated protein kinase 6  / complex / reaction
 ENSG00000159216 RUNX1 / Q01196 / runt related transcription factor 1  / complex / reaction






 

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