ENSG00000005243


Homo sapiens

Features
Gene ID: ENSG00000005243
  
Biological name :COPZ2
  
Synonyms : coatomer protein complex subunit zeta 2 / COPZ2 / Q9P299
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48026167
Gene end: 48038030
  
Corresponding Affymetrix probe sets: 219561_at (Human Genome U133 Plus 2.0 Array)   235897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463841
Ensembl peptide - ENSP00000480707
Ensembl peptide - ENSP00000464484
Ensembl peptide - ENSP00000462035
Ensembl peptide - ENSP00000463413
Ensembl peptide - ENSP00000463581
Ensembl peptide - ENSP00000463687
NCBI entrez gene - 51226     See in Manteia.
OMIM - 615526
RefSeq - NM_016429
RefSeq - XM_011524874
RefSeq Peptide - NP_057513
swissprot - A0A0G2JLH9
swissprot - J3QS21
swissprot - Q9P299
swissprot - J3QQQ5
swissprot - J3KRJ9
swissprot - J3QL73
swissprot - J3QLS7
Ensembl - ENSG00000005243
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Copz2ENSMUSG00000018672Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
COPZ1 / P61923 / coatomer protein complex subunit zeta 1ENSG0000011148162


Protein motifs (from Interpro)
Interpro ID Name
 IPR011012  Longin-like domain superfamily
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport NAS
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network NAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030126 COPI vesicle coat IDA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129083 COPB1 / P53618 / coatomer protein complex subunit beta 1  / complex
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000105669 COPE / O14579 / coatomer protein complex subunit epsilon  / complex
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / reaction / complex
 ENSG00000174903 RAB1B / Q9H0U4 / RAB1B, member RAS oncogene family  / reaction / complex
 ENSG00000181789 COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1  / complex
 ENSG00000158623 COPG2 / Q9UBF2 / coatomer protein complex subunit gamma 2  / complex
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / reaction / complex






 

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