ENSG00000174903


Homo sapiens

Features
Gene ID: ENSG00000174903
  
Biological name :RAB1B
  
Synonyms : Q9H0U4 / RAB1B / RAB1B, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 66268533
Gene end: 66277492
  
Corresponding Affymetrix probe sets: 220964_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310226
Ensembl peptide - ENSP00000435195
NCBI entrez gene - 81876     See in Manteia.
OMIM - 612565
RefSeq - NM_030981
RefSeq - XM_017018378
RefSeq Peptide - NP_112243
swissprot - E9PLD0
swissprot - Q9H0U4
Ensembl - ENSG00000174903
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:171927ENSDARG00000033056Danio rerio
 Rab1bENSMUSG00000024870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB1A / P62820 / RAB1A, member RAS oncogene familyENSG0000013806993
RAB35 / Q15286 / RAB35, member RAS oncogene familyENSG0000011173753
RAB43 / Q86YS6 / RAB43, member RAS oncogene familyENSG0000017278045
RAB19 / A4D1S5 / RAB19, member RAS oncogene familyENSG0000014695545
RAB30 / Q15771 / RAB30, member RAS oncogene familyENSG0000013750243
RAB26 / Q9ULW5 / RAB26, member RAS oncogene familyENSG0000016796442
Q14088 / RAB33A / RAB33A, member RAS oncogene familyENSG0000013459440
Q96S21 / RAB40C / RAB40C, member RAS oncogene familyENSG0000019756240
Q9H082 / RAB33B / RAB33B, member RAS oncogene familyENSG0000017200739
Q12829 / RAB40B / RAB40B, member RAS oncogene familyENSG0000014154238
RAB37 / Q96AX2 / RAB37, member RAS oncogene familyENSG0000017279438
P0C0E4 / RAB40AL / RAB40A likeENSG0000010212837
Q8WXH6 / RAB40A / RAB40A, member RAS oncogene familyENSG0000017247636


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019068 virion assembly IGI
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:1903020 positive regulation of glycoprotein metabolic process IGI
 biological_processGO:2000785 regulation of autophagosome assembly IMP
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane TAS
 cellular_componentGO:0034045 phagophore assembly site membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129083 COPB1 / P53618 / coatomer protein complex subunit beta 1  / reaction / complex
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex / reaction
 ENSG00000111481 COPZ1 / P61923 / coatomer protein complex subunit zeta 1  / complex / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / reaction / complex
 ENSG00000105669 COPE / O14579 / coatomer protein complex subunit epsilon  / complex / reaction
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex / reaction
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / complex / reaction
 ENSG00000181789 COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1  / complex / reaction
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex / reaction
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / complex / reaction
 ENSG00000158623 COPG2 / Q9UBF2 / coatomer protein complex subunit gamma 2  / complex / reaction
 ENSG00000005243 COPZ2 / Q9P299 / coatomer protein complex subunit zeta 2  / complex / reaction
 ENSG00000125875 Q96BZ9 / TBC1D20 / TBC1 domain family member 20  / complex / reaction






 

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