ENSMUSG00000024870


Mus musculus

Features
Gene ID: ENSMUSG00000024870
  
Biological name :Rab1b
  
Synonyms : Q9D1G1 / Rab1b / RAB1B, member RAS oncogene family
  
Possible biological names infered from orthology : Q9H0U4
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 5099207
Gene end: 5106996
  
Corresponding Affymetrix probe sets: 10464924 (MoGene1.0st)   1424064_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025804
NCBI entrez gene - 76308     See in Manteia.
MGI - MGI:1923558
RefSeq - NM_029576
RefSeq Peptide - NP_083852
swissprot - Q0PD66
swissprot - Q9D1G1
Ensembl - ENSMUSG00000024870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:171927ENSDARG00000033056Danio rerio
 RAB1BENSG00000174903Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab1 / P62821 / Ras-related protein Rab-1A / RAB1A* / P62820* / RAB1A, member RAS oncogene family*ENSMUSG0000002014992
Rab35 / Q6PHN9 / RAB35, member RAS oncogene family / Q15286*ENSMUSG0000002951853
Rab19 / P35294 / Ras-related protein Rab-19 / A4D1S5* / RAB19, member RAS oncogene family*ENSMUSG0000002992346
Rab43 / Q8CG50 / RAB43, member RAS oncogene family / Q86YS6*ENSMUSG0000003005543
Rab30 / Q923S9 / RAB30, member RAS oncogene family / Q15771*ENSMUSG0000003064343
Rab26 / Q504M8 / RAB26, member RAS oncogene family / Q9ULW5*ENSMUSG0000007965742
Rab37 / RAB37, member RAS oncogene family / Q96AX2*ENSMUSG0000002073240
Q8VHQ4 / Rab40c / Rab40C, member RAS oncogene family / Q96S21*ENSMUSG0000002573040
P97950 / Rab33a / RAB33A, member RAS oncogene family / Q14088*ENSMUSG0000003110440
Rab40b / Rab40B, member RAS oncogene family / Q12829* / RAB40A* / Q8WXH6* / P0C0E4* / RAB40AL* / RAB40A like* / RAB40A, member RAS oncogene family*ENSMUSG0000002517038
O35963 / Rab33b / RAB33B, member RAS oncogene family / Q9H082*ENSMUSG0000002773938


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019068 virion assembly IEA
 biological_processGO:1903020 positive regulation of glycoprotein metabolic process IEA
 biological_processGO:2000785 regulation of autophagosome assembly IEA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0034045 phagophore assembly site membrane ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding ISO


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Sprntm1Geno/Sprntm1Geno
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018672 Copz2 / Q9JHH9 / Coatomer subunit zeta-2 / Q9P299* / coatomer protein complex subunit zeta 2*  / complex / reaction
 ENSMUSG00000026553 Copa / Q8CIE6 / Coatomer subunit alpha Xenin Proxenin / P53621* / coatomer protein complex subunit alpha*  / complex / reaction
 ENSMUSG00000060992 Copz1 / P61924 / Coatomer subunit zeta-1 / P61923* / coatomer protein complex subunit zeta 1*  / complex / reaction
 ENSMUSG00000030754 Copb1 / Q9JIF7 / Coatomer subunit beta / P53618* / coatomer protein complex subunit beta 1*  / complex / reaction
 ENSMUSG00000032458 Copb2 / O55029 / Coatomer subunit beta / P35606* / coatomer protein complex subunit beta 2*  / complex / reaction
 ENSMUSG00000027465 Q9D9I4 / Tbc1d20 / TBC1 domain family member 20 / Q96BZ9*  / complex / reaction
 ENSMUSG00000029407 Uso1 / Q9Z1Z0 / USO1 vesicle docking factor / O60763* / USO1 vesicle transport factor*  / reaction / complex
 ENSMUSG00000030058 Copg1 / Q9QZE5 / Coatomer subunit gamma-1 / Q9Y678* / coatomer protein complex subunit gamma 1*  / complex / reaction
 ENSMUSG00000055681 Cope / O89079 / Coatomer subunit epsilon / O14579* / coatomer protein complex subunit epsilon*  / reaction / complex
 ENSMUSG00000025607 Copg2 / Q9QXK3 / Coatomer subunit gamma-2 / Q9UBF2* / coatomer protein complex subunit gamma 2*  / complex / reaction
 ENSMUSG00000032096 Arcn1 / Q5XJY5 / Coatomer subunit delta / P48444* / archain 1*  / reaction / complex
 ENSMUSG00000021877 Arf4 / P61750 / ADP-ribosylation factor 4 / P18085*  / reaction / complex






 

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