ENSMUSG00000030055


Mus musculus

Features
Gene ID: ENSMUSG00000030055
  
Biological name :Rab43
  
Synonyms : Q8CG50 / Rab43 / RAB43, member RAS oncogene family
  
Possible biological names infered from orthology : Q86YS6
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: D1
Gene start: 87788853
Gene end: 87812164
  
Corresponding Affymetrix probe sets: 10546056 (MoGene1.0st)   1425333_at (Mouse Genome 430 2.0 Array)   1430163_at (Mouse Genome 430 2.0 Array)   1451670_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032134
Ensembl peptide - ENSMUSP00000032135
Ensembl peptide - ENSMUSP00000077716
NCBI entrez gene - 69834     See in Manteia.
MGI - MGI:1917084
RefSeq - NM_001039394
RefSeq - NM_133717
RefSeq Peptide - NP_001034483
RefSeq Peptide - NP_598478
swissprot - Q91Z34
swissprot - Q0PD10
swissprot - Q8CG50
swissprot - D3Z444
Ensembl - ENSMUSG00000030055
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab43ENSDARG00000059404Danio rerio
 RAB43ENSGALG00000005021Gallus gallus
 RAB43ENSG00000172780Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab19 / P35294 / Ras-related protein Rab-19 / A4D1S5* / RAB19, member RAS oncogene family*ENSMUSG0000002992354
Rab30 / Q923S9 / RAB30, member RAS oncogene family / Q15771*ENSMUSG0000003064347
Rab1b / Q9D1G1 / RAB1B, member RAS oncogene family / Q9H0U4*ENSMUSG0000002487041
Rab26 / Q504M8 / RAB26, member RAS oncogene family / Q9ULW5*ENSMUSG0000007965741
Rab1 / P62821 / Ras-related protein Rab-1A / RAB1A* / P62820* / RAB1A, member RAS oncogene family*ENSMUSG0000002014941
Rab37 / RAB37, member RAS oncogene family / Q96AX2*ENSMUSG0000002073238
O35963 / Rab33b / RAB33B, member RAS oncogene family / Q9H082*ENSMUSG0000002773937
Rab35 / Q6PHN9 / RAB35, member RAS oncogene family / Q15286*ENSMUSG0000002951837
Rab40b / Rab40B, member RAS oncogene family / Q12829* / RAB40A* / Q8WXH6* / P0C0E4* / RAB40AL* / RAB40A like* / RAB40A, member RAS oncogene family*ENSMUSG0000002517036
P97950 / Rab33a / RAB33A, member RAS oncogene family / Q14088*ENSMUSG0000003110435
Q8VHQ4 / Rab40c / Rab40C, member RAS oncogene family / Q96S21*ENSMUSG0000002573035


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0019068 virion assembly IEA
 biological_processGO:0035526 retrograde transport, plasma membrane to Golgi ISO
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0090382 phagosome maturation ISO
 biological_processGO:1901998 toxin transport IMP
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045335 phagocytic vesicle ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002455 abnormal dendritic cell antigen presentation "impairment of these specialized cells to process and present antigen to T lymphoytes" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Dckm1Btlr/Dck+
Genetic Background: C57BL/6J-Dckm1Btlr

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039046 Q80XC3 / Usp6nl / USP6 N-terminal like / Q92738*  / complex / reaction






 

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