ENSMUSG00000030058


Mus musculus

Features
Gene ID: ENSMUSG00000030058
  
Biological name :Copg1
  
Synonyms : Coatomer subunit gamma-1 / Copg1 / Q9QZE5
  
Possible biological names infered from orthology : coatomer protein complex subunit gamma 1 / Q9Y678
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: D1
Gene start: 87887814
Gene end: 87913595
  
Corresponding Affymetrix probe sets: 10539822 (MoGene1.0st)   10338196 (MoGene1.0st)   10338339 (MoGene1.0st)   10338567 (MoGene1.0st)   10338578 (MoGene1.0st)   10338681 (MoGene1.0st)   10338811 (MoGene1.0st)   10339062 (MoGene1.0st)   10339153 (MoGene1.0st)   10339462 (MoGene1.0st)   10339766 (MoGene1.0st)   10340039 (MoGene1.0st)   10340511 (MoGene1.0st)   10340716 (MoGene1.0st)   10340958 (MoGene1.0st)   10341427 (MoGene1.0st)   10341520 (MoGene1.0st)   10342436 (MoGene1.0st)   10342636 (MoGene1.0st)   10342728 (MoGene1.0st)   10342893 (MoGene1.0st)   10342938 (MoGene1.0st)   10343064 (MoGene1.0st)   10343404 (MoGene1.0st)   10343727 (MoGene1.0st)   10343974 (MoGene1.0st)   10344093 (MoGene1.0st)   10344309 (MoGene1.0st)   10344323 (MoGene1.0st)   10339079 (MoGene1.0st)   10339572 (MoGene1.0st)   10341098 (MoGene1.0st)   10341505 (MoGene1.0st)   10341510 (MoGene1.0st)   10341697 (MoGene1.0st)   10341704 (MoGene1.0st)   10342164 (MoGene1.0st)   10342818 (MoGene1.0st)   10343033 (MoGene1.0st)   10343191 (MoGene1.0st)   10343989 (MoGene1.0st)   10344226 (MoGene1.0st)   1415670_at (Mouse Genome 430 2.0 Array)   1416017_at (Mouse Genome 430 2.0 Array)   1429575_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050858
Ensembl peptide - ENSMUSP00000109237
NCBI entrez gene - 54161     See in Manteia.
MGI - MGI:1858696
RefSeq - NM_201244
RefSeq - NM_017477
RefSeq Peptide - NP_059505
RefSeq Peptide - NP_957696
swissprot - Q7TNQ1
swissprot - Q9QZE5
Ensembl - ENSMUSG00000030058
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPG1ENSGALG00000005869Gallus gallus
 COPG1ENSG00000181789Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Copg2 / Q9QXK3 / Coatomer subunit gamma-2 / Q9UBF2* / coatomer protein complex subunit gamma 2*ENSMUSG0000002560781


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR009028  Coatomer/calthrin adaptor appendage, C-terminal subdomain
 IPR011989  Armadillo-like helical
 IPR013040  Coatomer, gamma subunit, appendage, Ig-like subdomain
 IPR013041  Clathrin adaptor, appendage, Ig-like subdomain superfamily
 IPR016024  Armadillo-type fold
 IPR017106  Coatomer gamma subunit
 IPR032154  Coatomer subunit gamma, C-terminal
 IPR037067  Coatomer, gamma subunit, appendage domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IEA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005488 binding IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018672 Copz2 / Q9JHH9 / Coatomer subunit zeta-2 / Q9P299* / coatomer protein complex subunit zeta 2*  / complex
 ENSMUSG00000026553 Copa / Q8CIE6 / Coatomer subunit alpha Xenin Proxenin / P53621* / coatomer protein complex subunit alpha*  / complex
 ENSMUSG00000024870 Rab1b / Q9D1G1 / RAB1B, member RAS oncogene family / Q9H0U4*  / complex / reaction
 ENSMUSG00000021877 Arf4 / P61750 / ADP-ribosylation factor 4 / P18085*  / complex / reaction
 ENSMUSG00000029407 Uso1 / Q9Z1Z0 / USO1 vesicle docking factor / O60763* / USO1 vesicle transport factor*  / reaction / complex
 ENSMUSG00000032096 Arcn1 / Q5XJY5 / Coatomer subunit delta / P48444* / archain 1*  / complex
 ENSMUSG00000032458 Copb2 / O55029 / Coatomer subunit beta / P35606* / coatomer protein complex subunit beta 2*  / complex
 ENSMUSG00000030754 Copb1 / Q9JIF7 / Coatomer subunit beta / P53618* / coatomer protein complex subunit beta 1*  / complex
 ENSMUSG00000055681 Cope / O89079 / Coatomer subunit epsilon / O14579* / coatomer protein complex subunit epsilon*  / complex
 ENSMUSG00000060992 Copz1 / P61924 / Coatomer subunit zeta-1 / P61923* / coatomer protein complex subunit zeta 1*  / complex






 

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