ENSG00000105669


Homo sapiens

Features
Gene ID: ENSG00000105669
  
Biological name :COPE
  
Synonyms : coatomer protein complex subunit epsilon / COPE / O14579
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 18899514
Gene end: 18919397
  
Corresponding Affymetrix probe sets: 201264_at (Human Genome U133 Plus 2.0 Array)   220469_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343134
Ensembl peptide - ENSP00000469035
Ensembl peptide - ENSP00000471034
Ensembl peptide - ENSP00000262812
Ensembl peptide - ENSP00000345674
NCBI entrez gene - 11316     See in Manteia.
OMIM - 606942
RefSeq - XM_011527656
RefSeq - NM_001330469
RefSeq - NM_007263
RefSeq - NM_199442
RefSeq - NM_199444
RefSeq - XM_011527655
RefSeq Peptide - NP_955474
RefSeq Peptide - NP_009194
RefSeq Peptide - NP_001317398
RefSeq Peptide - NP_955476
swissprot - M0QXB4
swissprot - M0R061
swissprot - O14579
Ensembl - ENSG00000105669
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 copeENSDARG00000018562Danio rerio
 COPEENSGALG00000003153Gallus gallus
 CopeENSMUSG00000055681Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006822  Coatomer, epsilon subunit
 IPR011990  Tetratricopeptide-like helical domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IEA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030126 COPI vesicle coat IBA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0030137 COPI-coated vesicle IEA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129083 COPB1 / P53618 / coatomer protein complex subunit beta 1  / complex
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex
 ENSG00000111481 COPZ1 / P61923 / coatomer protein complex subunit zeta 1  / complex
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / complex / reaction
 ENSG00000174903 RAB1B / Q9H0U4 / RAB1B, member RAS oncogene family  / reaction / complex
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / complex / reaction
 ENSG00000158623 COPG2 / Q9UBF2 / coatomer protein complex subunit gamma 2  / complex
 ENSG00000005243 COPZ2 / Q9P299 / coatomer protein complex subunit zeta 2  / complex
 ENSG00000181789 COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1  / complex






 

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