ENSDARG00000056695


Danio rerio

Features
Gene ID: ENSDARG00000056695
  
Biological name :phc2a
  
Synonyms : phc2a / polyhomeotic homolog 2a (Drosophila) / Q8QHL5
  
Possible biological names infered from orthology : PHC2 / polyhomeotic homolog 2 / Polyhomeotic-like protein 2 / Q8IXK0 / Q9QWH1
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 22063484
Gene end: 22130778
  
Corresponding Affymetrix probe sets: Dr.4649.1.A1_a_at (Zebrafish Array)   NM_152958_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000118477
Ensembl peptide - ENSDARP00000054361
Ensembl peptide - ENSDARP00000073668
Ensembl peptide - ENSDARP00000117469
NCBI entrez gene - 171465     See in Manteia.
RefSeq - NM_001136488
RefSeq - NM_152958
RefSeq - XM_005162144
RefSeq Peptide - NP_001129960
RefSeq Peptide - NP_694490
swissprot - Q8QHL5
swissprot - F1QNP6
swissprot - E9QIS7
ZFIN ID - ZDB-GENE-020312-1
Ensembl - ENSDARG00000056695
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039532Gallus gallus
 PHC2ENSG00000134686Homo sapiens
 Phc2ENSMUSG00000028796Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
phc2b / polyhomeotic homolog 2b (Drosophila) / PHC2* / Q8IXK0* / Q9QWH1* / polyhomeotic homolog 2* / Polyhomeotic-like protein 2 *ENSDARG0000001322456
phc1 / polyhomeotic homolog 1 / P78364* / Mus musculus polyhomeotic 1 (Phc1), transcript variant 5, mRNA.*ENSDARG0000000297135
si:ch211-230g15.5ENSDARG0000007916732
samd11 / sterile alpha motif domain containing 11 / Q1RNF8* / Q96NU1* / Sterile alpha motif domain-containing protein 11 *ENSDARG0000007785217
samd7 / sterile alpha motif domain containing 7 / Q7Z3H4* / Q8C8Y5* / Sterile alpha motif domain-containing protein 7 *ENSDARG0000006035417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR012313  Zinc finger, FCS-type
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0031519 PcG protein complex ISS
 cellular_componentGO:0035102 PRC1 complex ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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