ENSMUSG00000028796


Mus musculus

Features
Gene ID: ENSMUSG00000028796
  
Biological name :Phc2
  
Synonyms : Phc2 / Polyhomeotic-like protein 2 / Q9QWH1
  
Possible biological names infered from orthology : polyhomeotic homolog 2 / Q8IXK0
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.2
Gene start: 128654702
Gene end: 128752881
  
Corresponding Affymetrix probe sets: 10508351 (MoGene1.0st)   1416048_at (Mouse Genome 430 2.0 Array)   1437239_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113875
Ensembl peptide - ENSMUSP00000123307
Ensembl peptide - ENSMUSP00000120468
Ensembl peptide - ENSMUSP00000118298
Ensembl peptide - ENSMUSP00000117688
Ensembl peptide - ENSMUSP00000117163
Ensembl peptide - ENSMUSP00000116333
Ensembl peptide - ENSMUSP00000030588
Ensembl peptide - ENSMUSP00000101689
Ensembl peptide - ENSMUSP00000101690
NCBI entrez gene - 54383     See in Manteia.
MGI - MGI:1860454
RefSeq - XM_011240576
RefSeq - XM_006503234
RefSeq - XM_006503238
RefSeq - XM_006503237
RefSeq - XM_006503236
RefSeq - NM_001195083
RefSeq - NM_001195130
RefSeq - NM_018774
RefSeq - XM_017320320
RefSeq - XM_006503235
RefSeq Peptide - NP_001182012
RefSeq Peptide - NP_001182059
RefSeq Peptide - NP_061244
swissprot - Q9QWH1
swissprot - D6REH8
swissprot - B1AS97
swissprot - B1ASA0
swissprot - B1ASA1
swissprot - B1ASA2
swissprot - B1ASA3
Ensembl - ENSMUSG00000028796
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phc2aENSDARG00000056695Danio rerio
 phc2bENSDARG00000013224Danio rerio
 ENSGALG00000039532Gallus gallus
 PHC2ENSG00000134686Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phc3 / Q8CHP6 / Polyhomeotic-like protein 3 / Q8NDX5* / polyhomeotic homolog 3*ENSMUSG0000003765242
Phc1 / Mus musculus polyhomeotic 1 (Phc1), transcript variant 5, mRNA. / P78364* / polyhomeotic homolog 1*ENSMUSG0000004066938
Q1RNF8 / Samd11 / Sterile alpha motif domain-containing protein 11 / Q96NU1* / sterile alpha motif domain containing 11*ENSMUSG0000009635110
Samd7 / Q8C8Y5 / Sterile alpha motif domain-containing protein 7 / Q7Z3H4* / sterile alpha motif domain containing 7*ENSMUSG000000518609


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR012313  Zinc finger, FCS-type
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IGI
 cellular_componentGO:0000792 heterochromatin IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000030 abnormal tympanic ring morphology "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
Show

Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000078 abnormal supraoccipital bone morphology "malformed upper part of the occipital bone" [J:61509]
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Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000079 abnormal basioccipital bone morphology "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000080 abnormal exoccipital bone morphology "malformed lateral part of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000154 rib fusion "appearance of one or more ribs as a single structure" [J:62022, J:62023]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
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Allelic Composition: Phc2tm1Hko/Phc2+,Scmh1tm1Hko/Scmh1tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001689 incomplete somite formation "arrest of differentiation or patterning of the somites" [J:62882]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003036 vertebral transformation "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003056 abnormal hyoid bone "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004342 scapular bone foramen "presence of a hole in either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004449 absent presphenoid bone "absence of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004615 cervical vertebral transformation "homeotic transformation of any cervical vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004616 lumbar vertebral transformation "homeotic transformation of any lumbar vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004620 cervical vertebral fusion "the union of one or more cervical vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2tm2.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm2.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2tm3.1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Phc2tm3.1Hko/Phc2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004624 abnormal thoracic cage "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005269 abnormal occipital bone morphology "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Mtf2tm1.1Hko/Mtf2+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006337 abnormal first branchial arch morphology "anomaly in the structure of the first arch which contributes to development of mastication muscles, maxilla, mandible, incus, malleus, Meckel s cartilage, trigeminal nerve, and maxillary artery" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006338 abnormal second branchial arch morphology "anomaly in the structure of the second arch which contributes to the development of the stapes, styloid process, hyoid bone, stylohyoid ligament, muscles of facial expression, stapedius muscle, stylohyoid muscle, and lining of the palatine tonsils" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008008 early cellular replicative senescence "increase in the progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008146 asymmetric rib-sternum attachment "loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0008148 abnormal rib-sternum attachment "any anomaly in the in the normal joining of the ribs to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008271 abnormal bone ossification "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0010701 fusion of atlas and odontoid process "the large protuberance that projects upward from the cervical axis (C2), around which the cervical atlas normally rotates, is instead fused to elements of the atlas; the odontoid process may or may not remain attached to the axis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0010702 split cervical atlas 
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0010703 split cervical axis 
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Phc2tm1Hko/Phc2+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phc1tm1Os/Phc1+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Mtf2tm1.1Hko/Mtf2tm1.1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Mtf2tm1.1Hko/Mtf2+,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
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Allelic Composition: Cux1tm1Rhsc/Cux1tm1Rhsc
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0012062 small tail bud "decreased size or area of the primordial region of the embryo that arises to form the tail of the adult" [MGI:anna]
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Allelic Composition: Pcgf2tm1Hko/Pcgf2tm1Hko,Phc2tm1Hko/Phc2tm1Hko
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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