ENSDARG00000057121


Danio rerio

Features
Gene ID: ENSDARG00000057121
  
Biological name :c7b
  
Synonyms : c7b / complement component 7b
  
Possible biological names infered from orthology : C7 / complement C7 / complement component 7 / P10643
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 20901505
Gene end: 20915291
  
Corresponding Affymetrix probe sets: Dr.96.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114284
Ensembl peptide - ENSDARP00000148875
NCBI entrez gene - 570832     See in Manteia.
RefSeq - XM_021473424
RefSeq - XM_005161237
swissprot - F1QF24
ZFIN ID - ZDB-GENE-021120-1
Ensembl - ENSDARG00000057121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 C7ENSGALG00000014835Gallus gallus
 C7ENSG00000112936Homo sapiens
 C7ENSMUSG00000079105Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
c7a / complement component 7a / C7* / P10643* / complement C7* / complement component 7*ENSDARG0000004217247
c6 / complement component 6 / P13671* / complement C6*ENSDARG0000005711327
c6 / complement component 6 / P13671* / complement C6*ENSDARG0000009305225
c8b / complement component 8, beta polypeptide / P07358* / complement C8 beta chain*ENSDARG0000003951720
c8a / complement component 8, alpha polypeptide / P07357* / complement C8 alpha chain*ENSDARG0000003951619
c9 / complement component 9 / P02748* / complement C9*ENSDARG0000001631918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001862  Membrane attack complex component/perforin/complement C9
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR003884  Factor I / membrane attack complex
 IPR020863  Membrane attack complex component/perforin domain, conserved site
 IPR020864  Membrane attack complex component/perforin (MACPF) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0006956 complement activation IEA
 cellular_componentGO:0005579 membrane attack complex IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032098 c8g / complement component 8, gamma polypeptide / Q8VCG4* / P07360* / complement C8 gamma chain* / Complement component C8 gamma chain *  / reaction / complex
 ENSDARG00000039517 c8b / complement component 8, beta polypeptide / P07358* / complement C8 beta chain*  / reaction / complex
 ENSDARG00000053831 vtnb / vitronectin b / VTN* / P04004* / P29788* / AC002094.3* / vitronectin*  / complex / reaction
 ENSDARG00000021004 c5 / complement component 5 / P01031* / complement C5*  / complex / reaction
 ENSDARG00000039516 c8a / complement component 8, alpha polypeptide / P07357* / complement C8 alpha chain*  / complex / reaction
 ENSDARG00000016319 c9 / complement component 9 / P02748* / complement C9*  / complex / reaction






 

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