ENSMUSG00000079105


Mus musculus

Features
Gene ID: ENSMUSG00000079105
  
Biological name :C7
  
Synonyms : C7 / complement component 7
  
Possible biological names infered from orthology : complement C7 / P10643
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: A1
Gene start: 4988762
Gene end: 5063740
  
Corresponding Affymetrix probe sets: 10427436 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000106317
NCBI entrez gene - 109828     See in Manteia.
MGI - MGI:88235
RefSeq - NM_001243837
RefSeq Peptide - NP_001230766
swissprot - D3YXF5
Ensembl - ENSMUSG00000079105
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c7aENSDARG00000042172Danio rerio
 c7bENSDARG00000057121Danio rerio
 C7ENSGALG00000014835Gallus gallus
 C7ENSG00000112936Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C6 / complement component 6 / P13671* / complement C6*ENSMUSG0000002218125
C8a / Q8K182 / Complement component C8 alpha chain / P07357* / complement C8 alpha chain*ENSMUSG0000003503118
C8b / Q8BH35 / Complement component C8 beta chain / P07358* / complement C8 beta chain*ENSMUSG0000002965617
C9 / complement C9 / P02748*ENSMUSG0000002214915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001862  Membrane attack complex component/perforin/complement C9
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR003884  Factor I / membrane attack complex
 IPR020863  Membrane attack complex component/perforin domain, conserved site
 IPR020864  Membrane attack complex component/perforin (MACPF) domain
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR035976  Sushi/SCR/CCP superfamily
 IPR036055  LDL receptor-like superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily
 IPR037564  Complement component C7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0006956 complement activation IEA
 cellular_componentGO:0005579 membrane attack complex ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015083 C8g / Q8VCG4 / Complement component C8 gamma chain / P07360* / complement C8 gamma chain*  / complex / reaction
 ENSMUSG00000017344 Vtn / P29788 / vitronectin / P04004*  / complex / reaction
 ENSMUSG00000026874 Hc / P06684 / hemolytic complement / C5* / P01031* / complement C5*  / reaction / complex
 ENSMUSG00000022037 Clu / Q06890 / Clusterin Clusterin beta chain Clusterin alpha chain / P10909* / clusterin*  / complex / reaction
 ENSMUSG00000022149 C9 / complement C9 / P02748*  / complex / reaction
 ENSMUSG00000022181 C6 / complement component 6 / P13671* / complement C6*  / complex / reaction
 ENSMUSG00000029656 C8b / Q8BH35 / Complement component C8 beta chain / P07358* / complement C8 beta chain*  / reaction / complex
 ENSMUSG00000035031 C8a / Q8K182 / Complement component C8 alpha chain / P07357* / complement C8 alpha chain*  / complex / reaction
 ENSMUSG00000032679 Cd59a / O55186 / CD59A glycoprotein / CD59* / P13987* / AL049629.2* / CD59 glycoprotein * / CD59 molecule (CD59 blood group)*  / complex / reaction
 ENSMUSG00000068686 Cd59b / P58019 / CD59B glycoprotein / CD59* / P13987* / AL049629.2* / CD59 glycoprotein * / CD59 molecule (CD59 blood group)*  / reaction / complex






 

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