ENSMUSG00000015083


Mus musculus

Features
Gene ID: ENSMUSG00000015083
  
Biological name :C8g
  
Synonyms : C8g / Complement component C8 gamma chain / Q8VCG4
  
Possible biological names infered from orthology : complement C8 gamma chain / P07360
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 25498651
Gene end: 25501719
  
Corresponding Affymetrix probe sets: 10480751 (MoGene1.0st)   1451625_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015227
Ensembl peptide - ENSMUSP00000041855
NCBI entrez gene - 69379     See in Manteia.
MGI - MGI:88237
RefSeq - XM_011239171
RefSeq - NM_001271777
RefSeq - NM_027062
RefSeq Peptide - NP_081338
RefSeq Peptide - NP_001258706
swissprot - Q8VCG4
swissprot - Q9DAC2
Ensembl - ENSMUSG00000015083
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c8gENSDARG00000032098Danio rerio
 C8GENSGALG00000040644Gallus gallus
 C8GENSG00000176919Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002345  Lipocalin
 IPR002968  Alpha-1-microglobulin
 IPR012674  Calycin
 IPR022272  Lipocalin family conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006957 complement activation, alternative pathway IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0019835 cytolysis IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005579 membrane attack complex IEA
 molecular_functionGO:0019841 retinol binding IEA
 molecular_functionGO:0036094 small molecule binding IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026874 Hc / P06684 / hemolytic complement / C5* / P01031* / complement C5*  / reaction / complex
 ENSMUSG00000035031 C8a / Q8K182 / Complement component C8 alpha chain / P07357* / complement C8 alpha chain*  / complex
 ENSMUSG00000022181 C6 / complement component 6 / P13671* / complement C6*  / reaction / complex
 ENSMUSG00000079105 C7 / complement component 7 / P10643* / complement C7*  / reaction / complex
 ENSMUSG00000032679 Cd59a / O55186 / CD59A glycoprotein / CD59* / P13987* / AL049629.2* / CD59 glycoprotein * / CD59 molecule (CD59 blood group)*  / complex / reaction
 ENSMUSG00000068686 Cd59b / P58019 / CD59B glycoprotein / CD59* / P13987* / AL049629.2* / CD59 glycoprotein * / CD59 molecule (CD59 blood group)*  / complex / reaction
 ENSMUSG00000022149 C9 / complement C9 / P02748*  / complex / reaction
 ENSMUSG00000029656 C8b / Q8BH35 / Complement component C8 beta chain / P07358* / complement C8 beta chain*  / complex
 ENSMUSG00000017344 Vtn / P29788 / vitronectin / P04004*  / reaction / complex
 ENSMUSG00000022037 Clu / Q06890 / Clusterin Clusterin beta chain Clusterin alpha chain / P10909* / clusterin*  / reaction / complex






 

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