ENSDARG00000058821


Danio rerio

Features
Gene ID: ENSDARG00000058821
  
Biological name :sema5a
  
Synonyms : sema5a / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
  
Possible biological names infered from orthology : Q13591 / semaphorin 5A
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 16393302
Gene end: 16706981
  
Corresponding Affymetrix probe sets: Dr.1101.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137400
Ensembl peptide - ENSDARP00000150854
Ensembl peptide - ENSDARP00000144320
Ensembl peptide - ENSDARP00000076198
NCBI entrez gene - 561295     See in Manteia.
RefSeq - XM_005162619
RefSeq - XM_021470194
RefSeq - NM_001271670
RefSeq Peptide - NP_001258599
swissprot - A0A286YBG6
swissprot - A0A0R4IMM9
swissprot - F1R9L1
ZFIN ID - ZDB-GENE-030131-8969
Ensembl - ENSDARG00000058821
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEMA5AENSGALG00000028685Gallus gallus
 Q13591ENSG00000112902Homo sapiens
 Sema5aENSMUSG00000022231Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sema5ba / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba / SEMA5B* / Q60519* / Q9P283* / semaphorin 5B*ENSDARG0000006147155
sema5bb / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb / SEMA5B* / Q60519* / Q9P283* / semaphorin 5B*ENSDARG0000007564854
sema6dl / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like / SEMA6D* / Q76KF0* / Q8NFY4* / semaphorin 6D*ENSDARG0000001153322
sema6e / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E / Q9WTM3* / SEMA6C* / Q9H3T2* / semaphorin 6C* / sema domain, transmembrane domain (TM), and cytopla...ENSDARG0000000018921
sema6ba / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba / Q9H3T3* / SEMA6B* / O54951* / semaphorin 6B* / sema domain, transmembrane domain (TM), and cytop...ENSDARG0000003662620
sema6d / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D / Q9WTM3* / SEMA6C* / Q9H3T2* / semaphorin 6C* / sema domain, transmembrane domain (TM), and cytopla...ENSDARG0000000274819
sema6bb / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb / Q9H3T3* / SEMA6B* / O54951* / semaphorin 6B* / sema domain, transmembrane domain (TM), and cytop...ENSDARG0000006197618
sema7a / semaphorin 7A / O75326* / Q9QUR8* / semaphorin 7A (John Milton Hagen blood group)*ENSDARG0000007870713
si:ch211-113g11.6ENSDARG0000007044212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001627  Sema domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR027231  Semaphorin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048675 axon extension IMP
 biological_processGO:0050919 negative chemotaxis IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0038191 neuropilin binding IBA


Pathways (from Reactome)
Pathway description
Other semaphorin interactions
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001056 myotome myotome CaP motoneuron hypoplastic , abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032990 plxnb3 / plexin B3 / Q9QY40* / Q9ULL4*  / reaction / complex






 

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