ENSDARG00000061052


Danio rerio

Features
Gene ID: ENSDARG00000061052
  
Biological name :nipblb
  
Synonyms : F1QBY1 / nipblb / nipped-B homolog b (Drosophila)
  
Possible biological names infered from orthology : NIPBL / NIPBL, cohesin loading factor / Nipped-B-like protein / Q6KC79 / Q6KCD5
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 36475860
Gene end: 36547128
  
Corresponding Affymetrix probe sets: Dr.17238.2.A1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000081295
Ensembl peptide - ENSDARP00000098849
NCBI entrez gene - 794108     See in Manteia.
RefSeq - NM_001161447
RefSeq - XM_009305569
RefSeq Peptide - NP_001154919
swissprot - F1QBY1
ZFIN ID - ZDB-GENE-030131-6070
Ensembl - ENSDARG00000061052
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000003605Gallus gallus
 NIPBLLENSGALG00000039023Gallus gallus
 NIPBLENSG00000164190Homo sapiens
 NipblENSMUSG00000022141Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nipbla / nipped-B homolog a (Drosophila) / NIPBL* / Q6KC79* / Q6KCD5* / Nipped-B-like protein * / NIPBL, cohesin loading factor*ENSDARG0000009827258


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024986  Sister chromatid cohesion C-terminal domain
 IPR026003  HEAT repeat associated with sister chromatid cohesion protein
 IPR033031  SCC2/Nipped-B family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003146 heart jogging IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006412 translation IGI
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0007507 heart development IGI
 biological_processGO:0009303 rRNA transcription IGI
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0035118 embryonic pectoral fin morphogenesis IGI
 biological_processGO:0048565 digestive tract development IGI
 biological_processGO:0048589 developmental growth IGI
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IGI
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IMP
 biological_processGO:0070050 neuron cellular homeostasis IMP
 biological_processGO:0071733 transcriptional activation by promoter-enhancer looping IGI
 biological_processGO:0071921 cohesin loading ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003682 chromatin binding IEA


Pathways (from Reactome)
Pathway description
Cohesin Loading onto Chromatin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region decreased length , abnormal
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 ZFA:0001135 neural tube neural tube apoptotic , abnormal
neural tube apoptotic process increased occurrence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044144 wapla / WAPL cohesin release factor a / WAPL* / Q7Z5K2* / Q65Z40* / WAPL cohesin release factor*  / complex / reaction
 ENSDARG00000098272 nipbla / nipped-B homolog a (Drosophila) / NIPBL* / Q6KC79* / Q6KCD5* / Nipped-B-like protein * / NIPBL, cohesin loading factor*  / reaction
 ENSDARG00000061052 F1QBY1 / nipblb / nipped-B homolog b (Drosophila) / NIPBL* / Q6KCD5* / Q6KC79* / Nipped-B-like protein * / NIPBL, cohesin loading factor*  / reaction
 ENSDARG00000055022 pds5a / PDS5 cohesin associated factor A / Q29RF7*  / reaction / complex
 ENSDARG00000098897 pds5b / PDS5 cohesin associated factor B / Q4VA53* / Q9NTI5* / Mus musculus PDS5 cohesin associated factor B (Pds5b), transcript variant 2, mRNA.*  / complex / reaction






 

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