ENSDARG00000044144


Danio rerio

Features
Gene ID: ENSDARG00000044144
  
Biological name :wapla
  
Synonyms : wapla / WAPL cohesin release factor a
  
Possible biological names infered from orthology : Q65Z40 / Q7Z5K2 / WAPL / WAPL cohesin release factor
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 25856671
Gene end: 25885472
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000064816
Ensembl peptide - ENSDARP00000154785
NCBI entrez gene - 553345     See in Manteia.
swissprot - F1QU33
ZFIN ID - ZDB-GENE-131010-1
Ensembl - ENSDARG00000044144
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WAPLENSGALG00000001907Gallus gallus
 WAPLENSG00000062650Homo sapiens
 WaplENSMUSG00000041408Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
waplb / WAPL cohesin release factor b / WAPL* / Q7Z5K2* / Q65Z40* / WAPL cohesin release factor*ENSDARG0000002976860


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR012502  WAPL domain
 IPR022771  Wings apart-like protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007064 mitotic sister chromatid cohesion IBA
 biological_processGO:0045132 meiotic chromosome segregation IBA
 biological_processGO:0060623 regulation of chromosome condensation IBA
 biological_processGO:0071922 regulation of cohesin loading IBA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014685 esco2 / Q5SPR8 / establishment of sister chromatid cohesion N-acetyltransferase 2 / Q8CIB9* / Q56NI9* / N-acetyltransferase ESCO2 *  / reaction
 ENSDARG00000058471 plk1 / polo-like kinase 1 (Drosophila) / P53350* / Q07832* / polo like kinase 1*  / reaction
 ENSDARG00000098272 nipbla / nipped-B homolog a (Drosophila) / NIPBL* / Q6KC79* / Q6KCD5* / Nipped-B-like protein * / NIPBL, cohesin loading factor*  / complex / reaction
 ENSDARG00000061052 F1QBY1 / nipblb / nipped-B homolog b (Drosophila) / NIPBL* / Q6KCD5* / Q6KC79* / Nipped-B-like protein * / NIPBL, cohesin loading factor*  / complex / reaction
 ENSDARG00000098897 pds5b / PDS5 cohesin associated factor B / Q4VA53* / Q9NTI5* / Mus musculus PDS5 cohesin associated factor B (Pds5b), transcript variant 2, mRNA.*  / complex / reaction
 ENSDARG00000035655 rad21b / RAD21 cohesin complex component b / RAD21* / Q61550* / O60216* / Double-strand-break repair * / RAD21 cohesin complex component*  / reaction
 ENSDARG00000055022 pds5a / PDS5 cohesin associated factor A / Q29RF7*  / complex / reaction
 ENSDARG00000044144 wapla / WAPL cohesin release factor a / WAPL* / Q7Z5K2* / Q65Z40* / WAPL cohesin release factor*  / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSDARG00000077057 esco1 / establishment of sister chromatid cohesion N-acetyltransferase 1 / Q5FWF5* / Q69Z69* / N-acetyltransferase ESCO1 *  / reaction






 

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