ENSDARG00000061948


Danio rerio

Features
Gene ID: ENSDARG00000061948
  
Biological name :amotl2b
  
Synonyms : amotl2b / angiomotin like 2b
  
Possible biological names infered from orthology : AMOTL2 / angiomotin like 2 / Angiomotin-like protein 2 / Q8K371 / Q9Y2J4
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 22851832
Gene end: 22861178
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000114222
NCBI entrez gene - 559784     See in Manteia.
RefSeq - NM_001077606
RefSeq - XM_005171208
RefSeq Peptide - NP_001071074
swissprot - B8A5S6
ZFIN ID - ZDB-GENE-061103-307
Ensembl - ENSDARG00000061948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000006483Gallus gallus
 AMOTL2ENSG00000114019Homo sapiens
 Amotl2ENSMUSG00000032531Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1YB07 / amotl2a / angiomotin like 2a / AMOTL2* / Q8K371* / Q9Y2J4* / angiomotin like 2* / Angiomotin-like protein 2 *ENSDARG0000006192344
amot / angiomotin / Q4VCS5*ENSDARG0000007833536
AMOTL1 / angiomotin like 1 / Q8IY63*ENSDARG0000001944232


Protein motifs (from Interpro)
Interpro ID Name
 IPR009114  Angiomotin
 IPR024646  Angiomotin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035912 dorsal aorta morphogenesis IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta closed , abnormal
dorsal aorta blood vessel lumenization decreased process quality , abnormal
dorsal aorta decreased diameter , abnormal
dorsal aorta constricted , abnormal
dorsal aorta endothelial cell morphogenesis decreased process quality , abnormal
dorsal aorta blood vessel endothelial cell decreased length , abnormal
dorsal aorta blood vessel endothelial cell malformed , abnormal
dorsal aorta blood vessel lumenization disrupted , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000368 integument integument actin cytoskeleton morphology , abnormal
integument filamentous actin structure , abnormal
integument epithelial cell shape , abnormal
integument epithelial cell increased area , abnormal
Show

 ZFA:0001057 intersegmental vein intersegmental vein closed , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature blood circulation decreased occurrence , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel closed , abnormal
Show

 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell actin filament disorganized , abnormal
blood vessel endothelial cell filamentous actin punctate , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000068401 yap1 / Q1L8J7 / Yes-associated protein 1 / P46937* / P46938*  / complex / reaction
 ENSDARG00000067719 wwtr1 / WW domain containing transcription regulator 1 / Q9EPK5* / Q9GZV5*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr