ENSG00000114019


Homo sapiens

Features
Gene ID: ENSG00000114019
  
Biological name :AMOTL2
  
Synonyms : AMOTL2 / angiomotin like 2 / Q9Y2J4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.2
Gene start: 134355874
Gene end: 134375479
  
Corresponding Affymetrix probe sets: 203002_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421521
Ensembl peptide - ENSP00000427482
Ensembl peptide - ENSP00000427292
Ensembl peptide - ENSP00000427184
Ensembl peptide - ENSP00000425475
Ensembl peptide - ENSP00000424910
Ensembl peptide - ENSP00000424765
Ensembl peptide - ENSP00000422658
Ensembl peptide - ENSP00000249883
Ensembl peptide - ENSP00000409999
NCBI entrez gene - 51421     See in Manteia.
OMIM - 614658
RefSeq - XM_017006582
RefSeq - NM_001278683
RefSeq - NM_001278685
RefSeq - NM_016201
RefSeq - XM_006713654
RefSeq - XM_011512881
RefSeq - XM_017006580
RefSeq - XM_017006581
RefSeq Peptide - NP_001265612
RefSeq Peptide - NP_057285
RefSeq Peptide - NP_001265614
swissprot - D6RCL7
swissprot - D6RBK2
swissprot - D6RIC7
swissprot - D6RJA4
swissprot - Q9Y2J4
swissprot - D6RFG0
swissprot - D6RF61
Ensembl - ENSG00000114019
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A1YB07ENSDARG00000061923Danio rerio
 amotl2bENSDARG00000061948Danio rerio
 ENSGALG00000006483Gallus gallus
 Amotl2ENSMUSG00000032531Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMOTL1 / Q8IY63 / angiomotin like 1ENSG0000016602540
AMOT / Q4VCS5 / angiomotinENSG0000012601640


Protein motifs (from Interpro)
Interpro ID Name
 IPR009114  Angiomotin
 IPR024646  Angiomotin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035329 hippo signaling TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137693 YAP1 / P46937 / Yes associated protein 1  / complex / reaction
 ENSG00000018408 WWTR1 / Q9GZV5 / WW domain containing transcription regulator 1  / reaction / complex






 

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