ENSG00000126016


Homo sapiens

Features
Gene ID: ENSG00000126016
  
Biological name :AMOT
  
Synonyms : AMOT / angiomotin / Q4VCS5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q23
Gene start: 112774503
Gene end: 112840815
  
Corresponding Affymetrix probe sets: 209521_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429013
Ensembl peptide - ENSP00000361026
Ensembl peptide - ENSP00000361027
Ensembl peptide - ENSP00000361030
Ensembl peptide - ENSP00000305557
NCBI entrez gene - 154796     See in Manteia.
OMIM - 300410
RefSeq - XM_017029289
RefSeq - NM_001113490
RefSeq - NM_133265
RefSeq - XM_005262087
RefSeq - XM_005262090
RefSeq - XM_011530875
RefSeq Peptide - NP_001106962
RefSeq Peptide - NP_573572
swissprot - E7ERM3
swissprot - Q4VCS5
swissprot - A6NP16
Ensembl - ENSG00000126016
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amotENSDARG00000078335Danio rerio
 AMOTENSGALG00000007952Gallus gallus
 AmotENSMUSG00000041688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMOTL1 / Q8IY63 / angiomotin like 1ENSG0000016602541
AMOTL2 / Q9Y2J4 / angiomotin like 2ENSG0000011401931


Protein motifs (from Interpro)
Interpro ID Name
 IPR009114  Angiomotin
 IPR024646  Angiomotin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0003365 establishment of cell polarity involved in ameboidal cell migration IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030334 regulation of cell migration IDA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0035329 hippo signaling IGI
 biological_processGO:0040019 positive regulation of embryonic development IEA
 biological_processGO:0042074 cell migration involved in gastrulation IEA
 biological_processGO:0043534 blood vessel endothelial cell migration IEA
 biological_processGO:0048514 blood vessel morphogenesis IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043532 angiostatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000018408 WWTR1 / Q9GZV5 / WW domain containing transcription regulator 1  / reaction / complex
 ENSG00000137693 YAP1 / P46937 / Yes associated protein 1  / complex / reaction






 

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