ENSG00000166025


Homo sapiens

Features
Gene ID: ENSG00000166025
  
Biological name :AMOTL1
  
Synonyms : AMOTL1 / angiomotin like 1 / Q8IY63
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q21
Gene start: 94706431
Gene end: 94876753
  
Corresponding Affymetrix probe sets: 225450_at (Human Genome U133 Plus 2.0 Array)   225459_at (Human Genome U133 Plus 2.0 Array)   228840_at (Human Genome U133 Plus 2.0 Array)   235277_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387739
Ensembl peptide - ENSP00000299004
Ensembl peptide - ENSP00000320968
NCBI entrez gene - 154810     See in Manteia.
OMIM - 614657
RefSeq - XM_011542628
RefSeq - NM_001301007
RefSeq - NM_130847
RefSeq - XM_005273798
RefSeq - XM_005273801
RefSeq - XM_011542626
RefSeq Peptide - NP_001287936
RefSeq Peptide - NP_570899
swissprot - F8WDH4
swissprot - Q8IY63
swissprot - A0A024R3A6
Ensembl - ENSG00000166025
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMOTL1ENSDARG00000019442Danio rerio
 AMOTL1ENSGALG00000017208Gallus gallus
 Amotl1ENSMUSG00000013076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMOT / Q4VCS5 / angiomotinENSG0000012601646
AMOTL2 / Q9Y2J4 / angiomotin like 2ENSG0000011401935


Protein motifs (from Interpro)
Interpro ID Name
 IPR009114  Angiomotin
 IPR024646  Angiomotin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003365 establishment of cell polarity involved in ameboidal cell migration IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035329 hippo signaling TAS
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137693 YAP1 / P46937 / Yes associated protein 1  / reaction / complex
 ENSG00000018408 WWTR1 / Q9GZV5 / WW domain containing transcription regulator 1  / complex / reaction






 

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