ENSMUSG00000013076


Mus musculus

Features
Gene ID: ENSMUSG00000013076
  
Biological name :Amotl1
  
Synonyms : Amotl1 / Angiomotin-like protein 1 / Q9D4H4
  
Possible biological names infered from orthology : angiomotin like 1 / Q8IY63
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A2
Gene start: 14541966
Gene end: 14645056
  
Corresponding Affymetrix probe sets: 10590918 (MoGene1.0st)   1428785_at (Mouse Genome 430 2.0 Array)   1431121_at (Mouse Genome 430 2.0 Array)   1455247_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152834
Ensembl peptide - ENSMUSP00000013220
Ensembl peptide - ENSMUSP00000152243
NCBI entrez gene - 75723     See in Manteia.
MGI - MGI:1922973
RefSeq - XM_006510670
RefSeq - XM_006510666
RefSeq - XM_006510667
RefSeq - XM_006510668
RefSeq - XM_006510669
RefSeq - NM_001081395
RefSeq Peptide - NP_001074864
swissprot - A0A1Y7VM69
swissprot - A0A1Y7VL02
swissprot - Q9D4H4
Ensembl - ENSMUSG00000013076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMOTL1ENSDARG00000019442Danio rerio
 AMOTL1ENSGALG00000017208Gallus gallus
 AMOTL1ENSG00000166025Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Amot / Q8VHG2 / Angiomotin / Q4VCS5*ENSMUSG0000004168844
Amotl2 / Q8K371 / Angiomotin-like protein 2 / Q9Y2J4* / angiomotin like 2*ENSMUSG0000003253133


Protein motifs (from Interpro)
Interpro ID Name
 IPR009114  Angiomotin
 IPR024646  Angiomotin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003365 establishment of cell polarity involved in ameboidal cell migration IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035329 hippo signaling ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IMP
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027803 Wwtr1 / Q9EPK5 / WW domain containing transcription regulator 1 / Q9GZV5*  / reaction / complex
 ENSMUSG00000053110 Yap1 / P46938 / yes-associated protein 1 / P46937*  / reaction / complex






 

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