ENSDARG00000068557


Danio rerio

Features
Gene ID: ENSDARG00000068557
  
Biological name :htr5ab
  
Synonyms : 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b / htr5ab
  
Possible biological names infered from orthology : 5-hydroxytryptamine receptor 5A / 5-hydroxytryptamine (serotonin) receptor 5A / HTR5A / P30966 / P47898
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 41080649
Gene end: 41102498
  
Corresponding Affymetrix probe sets: DrAffx.2.44.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000089964
NCBI entrez gene - 368475     See in Manteia.
swissprot - Q7ZZ32
ZFIN ID - ZDB-GENE-030616-574
Ensembl - ENSDARG00000068557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTR5AENSGALG00000006362Gallus gallus
 HTR5AENSG00000157219Homo sapiens
 Htr5aENSMUSG00000039106Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
htr5aa / 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a / HTR5A* / P47898* / P30966* / 5-hydroxytryptamine receptor 5A* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSDARG0000003886986
htr1fb / 5-hydroxytryptamine (serotonin) receptor 1Fb / HTR1F* / Q02284* / P30939* / 5-hydroxytryptamine receptor 1F* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSDARG0000005358036
htr1aa / 5-hydroxytryptamine (serotonin) receptor 1A a / HTR1A* / Q64264* / P08908* / 5-hydroxytryptamine receptor 1A* / 5-hydroxytryptamine (serotonin) receptor 1A*ENSDARG0000009374535
htr1d / 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled / P28221* / Q61224* / 5-hydroxytryptamine receptor 1D* / 5-hydroxytryptamine (serotonin) receptor 1D*ENSDARG0000005412434
htr1fa / 5-hydroxytryptamine (serotonin) receptor 1Fa / HTR1F* / Q02284* / P30939* / 5-hydroxytryptamine receptor 1F* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSDARG0000010986233
FO704724.1 / HTR7* / P34969* / 5-hydroxytryptamine receptor 7*ENSDARG0000009985432
htr7a / 5-hydroxytryptamine (serotonin) receptor 7a / HTR7* / P34969* / P32304* / 5-hydroxytryptamine receptor 7* / 5-hydroxytryptamine (serotonin) receptor 7*ENSDARG0000005694932
htr1b / 5-hydroxytryptamine (serotonin) receptor 1B / P28222* / P28334* / 5-hydroxytryptamine receptor 1B*ENSDARG0000005398732
htr1ab / 5-hydroxytryptamine (serotonin) receptor 1A bENSDARG0000005709832
htr7b / 5-hydroxytryptamine (serotonin) receptor 7bENSDARG0000002758731
adra1aa / adrenoceptor alpha 1Aa / ADRA1A* / P35348* / adrenoceptor alpha 1A*ENSDARG0000002872530
adra2c / Q90WY6 / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *ENSDARG0000006966930
htr7c / 5-hydroxytryptamine (serotonin) receptor 7cENSDARG0000009527230
adra2db / adrenergic, alpha-2D-, receptor bENSDARG0000005466730
adra1ab / adrenoceptor alpha 1Ab / ADRA1A* / P35348* / P97718* / adrenoceptor alpha 1A* / Alpha-1A adrenergic receptor *ENSDARG0000002763829
adra2b / adrenoceptor alpha 2B / P18089*ENSDARG0000010209629
adra2a / adrenoceptor alpha 2A / P08913*ENSDARG0000004084129
adra2da / adrenergic, alpha-2D-, receptor aENSDARG0000009127729
adra1d / adrenoceptor alpha 1D / P25100*ENSDARG0000002410129
adra1bb / adrenoceptor alpha 1Bb / ADRA1B* / P35368* / adrenoceptor alpha 1B*ENSDARG0000004117328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001397  5-Hydroxytryptamine 5A receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IBA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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