ENSDARG00000069450


Danio rerio

Features
Gene ID: ENSDARG00000069450
  
Biological name :gja5b
  
Synonyms : gap junction protein, alpha 5b / gja5b
  
Possible biological names infered from orthology : gap junction protein alpha 5 / GJA5 / P36382 / Q01231
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 47414734
Gene end: 47431453
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091879
NCBI entrez gene - 570445     See in Manteia.
RefSeq - NM_001034988
RefSeq Peptide - NP_001030160
swissprot - B3DID2
ZFIN ID - ZDB-GENE-050616-11
Ensembl - ENSDARG00000069450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000042735Gallus gallus
 GJA5ENSGALG00000039452Gallus gallus
 GJA5ENSG00000265107Homo sapiens
 Gja5ENSMUSG00000057123Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gja5a / gap junction protein, alpha 5a / GJA5* / P36382* / Q01231* / gap junction protein alpha 5*ENSDARG0000004006564
gja3 / gap junction protein, alpha 3 / Q64448* / Q9Y6H8*ENSDARG0000002188945
cx39.9 / connexin 39.9ENSDARG0000000408241
gja8b / gap junction protein alpha 8 paralog b / GJA8* / P28236* / P48165* / gap junction protein alpha 8*ENSDARG0000001507641
gja8a / gap junction protein alpha 8 paralog a / GJA8* / P28236* / P48165* / gap junction protein alpha 8*ENSDARG0000006945139
cx43 / O57474 / connexin 43ENSDARG0000004179939
cx52.7 / connexin 52.7 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000005779236
cx52.6 / connexin 52.6 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000003493036
cx52.9 / connexin 52.9 / GJA9* / P57773* / gap junction protein alpha 9*ENSDARG0000008645336
cx40.8 / connexin 40.8 / GJA1* / P23242* / P17302* / gap junction protein alpha 1*ENSDARG0000007119235
cx34.5 / connexin 34.5ENSDARG0000006941135
cx32.3 / connexin 32.3ENSDARG0000004178733
cx39.4 / connexin 39.4 / GJA4* / P35212* / P28235* / gap junction protein alpha 4*ENSDARG0000007035732
cx28.9 / connexin 28.9ENSDARG0000004179732
cx47.1 / connexin 47.1 / GJC2* / Q8BQU6* / Q5T442* / gap junction protein gamma 2*ENSDARG0000007389629
cx32.2 / Q7T047 / connexin 32.2ENSDARG0000007678929
cx43.4 / connexin 43.4ENSDARG0000000709928
cx28.1 / connexin 28.1ENSDARG0000004179228
cx44.2 / connexin 44.2 / si:dkey-91f15.8ENSDARG0000003420728
si:dkey-91f15.1ENSDARG0000009499026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002264  Gap junction alpha-5 protein (Cx40)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain
 IPR031862  Gap junction alpha-5 protein (Cx40), C-terminal
 IPR034634  Connexin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097324 melanocyte migration IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0055077 gap junction hemi-channel activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain acetylcholinesterase activity increased process quality , abnormal
Show

 ZFA:0000368 integument integument pigmentation disrupted , abnormal
Show

 ZFA:0001058 caudal fin caudal fin melanophore stripe spotted , abnormal
caudal fin melanophore stripe absent , abnormal
caudal fin melanocyte decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism spotted , abnormal
whole organism has fewer parts of type melanocyte , abnormal
whole organism dappled , abnormal
Show

 ZFA:0001162 anal fin anal fin has fewer parts of type melanocyte , abnormal
anal fin has fewer parts of type xanthophore , abnormal
anal fin spotted , abnormal
anal fin melanophore stripe patchy , abnormal
anal fin melanophore stripe undulate , abnormal
anal fin melanophore stripe spotted , abnormal
anal fin melanophore stripe absent , abnormal
anal fin melanocyte decreased amount , abnormal
Show

 ZFA:0001463 melanophore stripe melanophore stripe spatial pattern , abnormal
melanophore stripe spotted , abnormal
melanophore stripe absent , abnormal
melanophore stripe broken , abnormal
melanophore stripe irregular spatial pattern , abnormal
melanophore stripe patchy , abnormal
melanophore stripe increased width , abnormal
melanophore stripe undulate , abnormal
melanophore stripe disheveled , abnormal
melanophore stripe decreased width , abnormal
melanophore stripe morphology , abnormal
Show

 ZFA:0009090 pigment cell pigment cell spatial pattern , abnormal
pigment cell quality , abnormal
pigment cell irregular spatial pattern , abnormal
Show

 ZFA:0009091 melanocyte melanocyte disorganized , abnormal
melanocyte dispersed , abnormal
melanocyte distributed , abnormal
Show

 ZFA:0009198 xanthophore xanthophore absent , abnormal
Show

 ZFA:0009199 iridophore iridophore pigmentation process quality , abnormal
iridophore absent , abnormal
iridophore dispersed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr