ENSDARG00000074730


Danio rerio

Features
Gene ID: ENSDARG00000074730
  
Biological name :pkmyt1
  
Synonyms : pkmyt1 / protein kinase, membrane associated tyrosine/threonine 1
  
Possible biological names infered from orthology : Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase / Q99640 / Q9ESG9
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 14965587
Gene end: 15002619
  
Corresponding Affymetrix probe sets: Dr.11509.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000122987
Ensembl peptide - ENSDARP00000100899
NCBI entrez gene - 100049158     See in Manteia.
RefSeq - NM_001098196
RefSeq - XM_005156122
RefSeq Peptide - NP_001091666
swissprot - B1H1M4
ZFIN ID - ZDB-GENE-060810-80
Ensembl - ENSDARG00000074730
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKMYT1ENSG00000127564Homo sapiens
 Pkmyt1ENSMUSG00000023908Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wee1 / WEE1 G2 checkpoint kinase / P30291* / P47810* / WEE 1 homolog 1 (S. pombe)*ENSDARG0000009386421
wee2 / Q1LX51 / WEE1 homolog 2 (S. pombe) / Q66JT0* / P0C1S8* / WEE1 homolog 2*ENSDARG0000001271818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Polo-like kinase mediated events
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000058471 plk1 / polo-like kinase 1 (Drosophila) / P53350* / Q07832* / polo like kinase 1*  / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction






 

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contact: otassy@igbmc.fr