ENSDARG00000076302


Danio rerio

Features
Gene ID: ENSDARG00000076302
  
Biological name :DTX4
  
Synonyms : DTX4 / si:ch211-119e14.2
  
Possible biological names infered from orthology : deltex E3 ubiquitin ligase 4 / E3 ubiquitin-protein ligase DTX4 / Q6PDK8 / Q9Y2E6
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 18557939
Gene end: 18601206
  
Corresponding Affymetrix probe sets: Dr.18123.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000102662
Ensembl peptide - ENSDARP00000153314
NCBI entrez gene - 570481     See in Manteia.
RefSeq - NM_001127308
RefSeq Peptide - NP_001120780
swissprot - F1QI34
ZFIN ID - ZDB-GENE-160728-59
Ensembl - ENSDARG00000076302
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DTX4ENSGALG00000010835Gallus gallus
 DTX4ENSG00000110042Homo sapiens
 Dtx4ENSMUSG00000039982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dtx4 / deltex 4, E3 ubiquitin ligase / Q9Y2E6* / Q6PDK8* / deltex E3 ubiquitin ligase 4* / E3 ubiquitin-protein ligase DTX4 *ENSDARG0000007801677
dtx2 / deltex 2, E3 ubiquitin ligase / Q86UW9* / Q8R3P2* / deltex E3 ubiquitin ligase 2* / Probable E3 ubiquitin-protein ligase DTX2 *ENSDARG0000003293337
si:dkey-40c23.2ENSDARG0000007550417
si:dkey-40c23.2 / si:dkey-40c23.3ENSDARG0000010464916
zgc:66440 / DTX3* / Q80V91* / Q8N9I9* / deltex E3 ubiquitin ligase 3* / Probable E3 ubiquitin-protein ligase DTX3 *ENSDARG0000002576614
si:dkey-3h3.3ENSDARG0000006771814
si:dkey-40c23.1ENSDARG000000975929
si:ch73-78o10.1ENSDARG000000895118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004170  WWE domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018123  WWE domain, subgroup
 IPR018957  Zinc finger, C3HC4 RING-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activated NOTCH1 Transmits Signal to the Nucleus
Regulation of innate immune responses to cytosolic DNA
IRF3-mediated induction of type I IFN


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076251 irf3 / interferon regulatory factor 3 / P70671* / Q14653*  / complex / reaction
 ENSDARG00000091058 tmem173 / transmembrane protein 173 / Q3TBT3* / Q86WV6* / Stimulator of interferons protein *  / complex / reaction
 ENSDARG00000103095 tbk1 / TANK-binding kinase 1 / Q9UHD2*  / reaction / complex






 

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