ENSDARG00000076317


Danio rerio

Features
Gene ID: ENSDARG00000076317
  
Biological name :wu:fb72h05
  
Synonyms : plod3 / wu:fb72h05
  
Possible biological names infered from orthology : O60568 / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 / Q9R0E1
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 44843860
Gene end: 44879214
  
Corresponding Affymetrix probe sets: Dr.330.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000080199
Ensembl peptide - ENSDARP00000123997
Ensembl peptide - ENSDARP00000124969
NCBI entrez gene - 556077     See in Manteia.
RefSeq - NM_001044343
RefSeq Peptide - NP_001037808
swissprot - F8W3X8
swissprot - A3KNH4
swissprot - F8W5U8
ZFIN ID - ZDB-GENE-021031-4
ZFIN ID - ZDB-GENE-030131-1486
Ensembl - ENSDARG00000076317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLOD3ENSG00000106397Homo sapiens
 Plod3ENSMUSG00000004846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a / PLOD1* / Q9R0E2* / Q02809* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1*ENSDARG0000005974658
plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*ENSDARG0000001182158
si:ch211-13f8.2 / Q8IYK4* / Q6NVG7* / COLGALT2* / Procollagen galactosyltransferase 2 * / collagen beta(1-O)galactosyltransferase 2*ENSDARG0000007829914
colgalt2 / collagen beta(1-O)galactosyltransferase 2 / Q6NVG7* / Q8IYK4* / Procollagen galactosyltransferase 2 *ENSDARG0000001467014
cercam / cerebral endothelial cell adhesion molecule / A3KGW5* / Q5T4B2* / Inactive glycosyltransferase 25 family member 3 *ENSDARG0000007904914
A5PMF6 / COLGALT1 / si:ch211-114l13.7 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 * / collagen beta(1-O)galactosyltransferase 1*ENSDARG0000005827013
colgalt1 / collagen beta(1-O)galactosyltransferase 1 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 *ENSDARG0000007397413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001006  Procollagen-lysine 5-dioxygenase
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008475 procollagen-lysine 5-dioxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000029 hindbrain hindbrain quality , abnormal
hindbrain morphology , abnormal
Show

 ZFA:0000135 notochord notochord degenerate , abnormal
notochord undulate , abnormal
Show

 ZFA:0000155 somite somite quality , abnormal
somite morphology , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature contractility , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism movement behavioral quality , abnormal
Show

 ZFA:0001115 trunk trunk motor neuron axon guidance process quality , abnormal
Show

 ZFA:0005179 MiP motor neuron MiP motor neuron axon absent , abnormal
MiP motor neuron axon mislocalised , abnormal
Show

 ZFA:0005180 RoP motor neuron RoP motor neuron axon mislocalised , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell lacks parts or has fewer parts of type neural crest cell filopodium, abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon decreased length , abnormal
CaP motoneuron axon mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011821 plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*  / reaction
 ENSDARG00000059746 plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a / PLOD1* / Q9R0E2* / Q02809* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1*  / reaction
 ENSDARG00000076317 plod3 / wu:fb72h05 / O60568* / Q9R0E1* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3*  / complex / reaction






 

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