ENSDARG00000059746


Danio rerio

Features
Gene ID: ENSDARG00000059746
  
Biological name :plod1a
  
Synonyms : plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a
  
Possible biological names infered from orthology : PLOD1 / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 / Q02809 / Q9R0E2
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 47850073
Gene end: 47895817
  
Corresponding Affymetrix probe sets: Dr.7688.1.A1_at (Zebrafish Array)   NM_001077742_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000077830
Ensembl peptide - ENSDARP00000112909
NCBI entrez gene - 777635     See in Manteia.
RefSeq - NM_001077742
RefSeq Peptide - NP_001071210
swissprot - E9QCW2
swissprot - A8WIN7
ZFIN ID - ZDB-GENE-030131-3165
Ensembl - ENSDARG00000059746
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLOD1ENSGALG00000004531Gallus gallus
 PLOD1ENSG00000083444Homo sapiens
 Plod1ENSMUSG00000019055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*ENSDARG0000001182158
plod3 / wu:fb72h05 / O60568* / Q9R0E1* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3*ENSDARG0000007631758
A5PMF6 / COLGALT1 / si:ch211-114l13.7 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 * / collagen beta(1-O)galactosyltransferase 1*ENSDARG0000005827014
colgalt1 / collagen beta(1-O)galactosyltransferase 1 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 *ENSDARG0000007397414
colgalt2 / collagen beta(1-O)galactosyltransferase 2 / Q6NVG7* / Q8IYK4* / Procollagen galactosyltransferase 2 *ENSDARG0000001467013
si:ch211-13f8.2 / Q8IYK4* / Q6NVG7* / COLGALT2* / Procollagen galactosyltransferase 2 * / collagen beta(1-O)galactosyltransferase 2*ENSDARG0000007829913
cercam / cerebral endothelial cell adhesion molecule / A3KGW5* / Q5T4B2* / Inactive glycosyltransferase 25 family member 3 *ENSDARG0000007904913


Protein motifs (from Interpro)
Interpro ID Name
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033333 fin development IMP
 biological_processGO:0033334 fin morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008475 procollagen-lysine 5-dioxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001069 ventral fin fold ventral fin fold decreased size , abnormal
ventral fin fold malformed , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
Show

 ZFA:0005435 actinotrichium actinotrichium absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011821 plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*  / reaction
 ENSDARG00000059746 plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a / PLOD1* / Q9R0E2* / Q02809* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1*  / reaction / complex
 ENSDARG00000076317 plod3 / wu:fb72h05 / O60568* / Q9R0E1* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3*  / reaction






 

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