ENSDARG00000077130


Danio rerio

Features
Gene ID: ENSDARG00000077130
  
Biological name :bcl10
  
Synonyms : B cell CLL/lymphoma 10 / bcl10
  
Possible biological names infered from orthology : B-cell lymphoma/leukemia 10 / O95999 / Q9Z0H7
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 1945211
Gene end: 1954204
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000103460
NCBI entrez gene - 100334750     See in Manteia.
swissprot - E7F8A6
ZFIN ID - ZDB-GENE-100219-2
Ensembl - ENSDARG00000077130
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCL10ENSGALG00000028935Gallus gallus
 BCL10ENSG00000142867Homo sapiens
 Bcl10ENSMUSG00000028191Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily
 IPR033238  B-cell lymphoma/leukemia 10/E10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032449 CBM complex IDA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Downstream TCR signaling
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021509 tab2 / Q5RFW2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q9NYJ8* / Q99K90* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / reaction / complex
 ENSDARG00000028058 traf6 / Q6IWL4 / TNF receptor-associated factor 6 / P70196* / Q9Y4K3*  / reaction / complex
 ENSDARG00000034173 prkcq / protein kinase C, theta / Q02111* / Q04759*  / complex
 ENSDARG00000116649 rpl15 / ube2e1 / ubiquitin-conjugating enzyme E2E 1 / Q96LR5* / P51965* / UBE2E2* / ubiquitin conjugating enzyme E2 E2*  / complex / reaction
 ENSDARG00000043484 ube2d2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / P62838* / P62837* / Ube2d2a* / ubiquitin conjugating enzyme E2 D2* / ubiquitin-conjugating enzyme E2D 2A*  / reaction / complex
 ENSDARG00000077130 bcl10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / reaction / complex / -
 ENSDARG00000038576 ube2d1b / ubiquitin-conjugating enzyme E2D 1b / UBE2D1* / P51668* / P61080* / ubiquitin conjugating enzyme E2 D1*  / reaction / complex
 ENSDARG00000018285 pdpk1b / 3-phosphoinositide dependent protein kinase 1b / PDPK1* / O15530* / Q9Z2A0* / 3-phosphoinositide dependent protein kinase 1*  / complex / reaction
 ENSDARG00000008748 ube2na / ubiquitin-conjugating enzyme E2Na / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction / complex
 ENSDARG00000067672 card9 / caspase recruitment domain family, member 9 / Q9H257*  / reaction / complex
 ENSDARG00000034670 ube2e2 / ubiquitin-conjugating enzyme E2E 2 / Q91W82* / Q96LR5* / UBE2E1* / P52482* / P51965* / ubiquitin conjugating enzyme E2 E1*  / reaction / complex
 ENSDARG00000045877 ube2nb / ubiquitin-conjugating enzyme E2Nb / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction / complex
 ENSDARG00000062063 tab3 / TGF-beta activated kinase 1/MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1 and MAP3K7 binding protein 3*  / complex / reaction
 ENSDARG00000077768 malt1 / MALT paracaspase 1 / Q2TBA3* / Q9UDY8* / MALT1 paracaspase* / Mucosa-associated lymphoid tissue lymphoma translocation *  / complex / reaction
 ENSDARG00000023958 rnf181 / Q7ZW78 / ring finger protein 181 / Q9CY62* / Q9P0P0* / Mus musculus ring finger protein 181 (Rnf181), transcript variant 11, mRNA.*  / reaction / complex






 

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