ENSDARG00000077588


Danio rerio

Features
Gene ID: ENSDARG00000077588
  
Biological name :pdgfc
  
Synonyms : pdgfc / platelet derived growth factor c
  
Possible biological names infered from orthology : platelet-derived growth factor, C polypeptide / Q8CI19 / Q9NRA1
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 35567321
Gene end: 35853647
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000069196
NCBI entrez gene - 560564     See in Manteia.
swissprot - E7FB33
ZFIN ID - ZDB-GENE-071217-2
Ensembl - ENSDARG00000077588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDGFCENSGALG00000009378Gallus gallus
 PDGFCENSG00000145431Homo sapiens
 PdgfcENSMUSG00000028019Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdgfd / platelet derived growth factor d / Q9GZP0*ENSDARG0000007767738


Protein motifs (from Interpro)
Interpro ID Name
 IPR000072  PDGF/VEGF domain
 IPR000859  CUB domain
 IPR029034  Cystine-knot cytokine
 IPR029817  Platelet-derived growth factor C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009790 embryo development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IBA
 biological_processGO:0030335 positive regulation of cell migration IBA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity IBA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023111 plg / plasminogen / LPA* / P08519* / P20918* / P00747* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*  / reaction
 ENSDARG00000077588 pdgfc / platelet derived growth factor c / Q8CI19* / Q9NRA1* / platelet-derived growth factor, C polypeptide*  / complex
 ENSDARG00000062707 plat / plasminogen activator, tissue / P11214* / P00750* / plasminogen activator, tissue type* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plas...  / reaction






 

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