ENSDARG00000077840


Danio rerio

Features
Gene ID: ENSDARG00000077840
  
Biological name :meis2b
  
Synonyms : meis2a / meis2b / Meis homeobox 2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 10098590
Gene end: 10120442
  
Corresponding Affymetrix probe sets: Dr.8217.1.S1_at (Zebrafish Array)   NM_130910_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000034815
Ensembl peptide - ENSDARP00000121019
NCBI entrez gene - 30066     See in Manteia.
RefSeq - XM_009294577
RefSeq - NM_130910
RefSeq Peptide - NP_570985
swissprot - Q9DDE0
ZFIN ID - ZDB-GENE-000210-23
ZFIN ID - ZDB-GENE-020122-2
Ensembl - ENSDARG00000077840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
meis2a / Meis homeobox 2a / MEIS2* / P97367* / O14770* / Meis homeobox 2* / Homeobox protein Meis2 *ENSDARG0000009824087
meis1b / Meis homeobox 1 b / MEIS1* / Q60954* / O00470* / Meis homeobox 1* / Homeobox protein Meis1 *ENSDARG0000001207880
meis1a / Meis homeobox 1 a / MEIS1* / Q60954* / O00470* / Meis homeobox 1* / Homeobox protein Meis1 *ENSDARG0000000293769
meis3 / myeloid ecotropic viral integration site 3 / P97368* / Q99687* / Meis homeobox 3* / Homeobox protein Meis3 *ENSDARG0000000279561
pknox2 / pbx/knotted 1 homeobox 2 / Q8BG99* / Q96KN3* / Homeobox protein PKNOX2 *ENSDARG0000005534938
pknox1.1 / pbx/knotted 1 homeobox 1.1 / O70477* / P55347* / PKNOX1* / PBX/knotted 1 homeobox 1* / Homeobox protein PKNOX1 *ENSDARG0000001876534
pknox1.2 / pbx/knotted 1 homeobox 1.2 / O70477* / P55347* / PKNOX1* / PBX/knotted 1 homeobox 1* / Homeobox protein PKNOX1 *ENSDARG0000003654234
tgif1 / TGFB-induced factor homeobox 1 / P70284* / Q15583*ENSDARG0000005933712
FO834857.1 / TGIF2* / Q9GZN2* / TGFB induced factor homeobox 2*ENSDARG000001128959


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR032453  Homeobox protein PKNOX/Meis, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart position , abnormal
heart decreased functionality , abnormal
Show

 ZFA:0001094 whole organism whole organism curvature , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head increased variability of size , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage fused with palatoquadrate cartilage , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage mislocalised , abnormal
cranial cartilage fused with cranial cartilage , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr