ENSDARG00000036542


Danio rerio

Features
Gene ID: ENSDARG00000036542
  
Biological name :pknox1.2
  
Synonyms : pbx/knotted 1 homeobox 1.2 / pknox1.2
  
Possible biological names infered from orthology : Homeobox protein PKNOX1 / O70477 / P55347 / PBX/knotted 1 homeobox 1 / PKNOX1
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 46963993
Gene end: 46984142
  
Corresponding Affymetrix probe sets: Dr.20995.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000110278
Ensembl peptide - ENSDARP00000111389
NCBI entrez gene - 170445     See in Manteia.
swissprot - B8A551
swissprot - E7FBG0
ZFIN ID - ZDB-GENE-020123-1
Ensembl - ENSDARG00000036542
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKNOX1ENSGALG00000016191Gallus gallus
 P55347ENSG00000160199Homo sapiens
 O70477ENSMUSG00000006705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pknox1.1 / pbx/knotted 1 homeobox 1.1 / O70477* / P55347* / PKNOX1* / PBX/knotted 1 homeobox 1* / Homeobox protein PKNOX1 *ENSDARG0000001876567
pknox2 / pbx/knotted 1 homeobox 2 / Q8BG99* / Q96KN3* / Homeobox protein PKNOX2 *ENSDARG0000005534957
meis2a / Meis homeobox 2a / MEIS2* / P97367* / O14770* / Meis homeobox 2* / Homeobox protein Meis2 *ENSDARG0000009824030
meis2a / meis2b / Meis homeobox 2bENSDARG0000007784030
meis1a / Meis homeobox 1 a / MEIS1* / Q60954* / O00470* / Meis homeobox 1* / Homeobox protein Meis1 *ENSDARG0000000293729
meis3 / myeloid ecotropic viral integration site 3 / P97368* / Q99687* / Meis homeobox 3* / Homeobox protein Meis3 *ENSDARG0000000279529
meis1b / Meis homeobox 1 b / MEIS1* / Q60954* / O00470* / Meis homeobox 1* / Homeobox protein Meis1 *ENSDARG0000001207829
tgif1 / TGFB-induced factor homeobox 1 / P70284* / Q15583*ENSDARG0000005933711
FO834857.1 / TGIF2* / Q9GZN2* / TGFB induced factor homeobox 2*ENSDARG0000011289510


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR032453  Homeobox protein PKNOX/Meis, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IMP
 biological_processGO:0060037 pharyngeal system development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000141 pectoral fin bud pectoral fin bud physical object quality , abnormal
Show

 ZFA:0001131 pharyngeal pouch 3 pharyngeal pouch 3 aplastic , abnormal
Show

 ZFA:0001132 pharyngeal pouch 6 pharyngeal pouch 6 aplastic , abnormal
Show

 ZFA:0001133 pharyngeal pouch 5 pharyngeal pouch 5 aplastic , abnormal
Show

 ZFA:0001134 pharyngeal pouch 4 pharyngeal pouch 4 aplastic , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Meckels cartilage malformed , abnormal
Show

 ZFA:0001228 pharyngeal arch 3 skeleton pharyngeal arch 3 skeleton decreased size , abnormal
Show

 ZFA:0001229 pharyngeal arch 7 skeleton pharyngeal arch 7 skeleton aplastic , abnormal
Show

 ZFA:0001230 pharyngeal arch 6 skeleton pharyngeal arch 6 skeleton aplastic , abnormal
Show

 ZFA:0001231 pharyngeal arch 4 skeleton pharyngeal arch 4 skeleton aplastic , abnormal
Show

 ZFA:0001232 pharyngeal arch 5 skeleton pharyngeal arch 5 skeleton aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased size , abnormal
ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 physical object quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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