ENSDARG00000079972


Danio rerio

Features
Gene ID: ENSDARG00000079972
  
Biological name :nfatc2b
  
Synonyms : nfatc2b / nuclear factor of activated T cells 2b
  
Possible biological names infered from orthology : NFATC2 / nuclear factor of activated T cells 2 / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 / Q13469 / Q60591
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 55221490
Gene end: 55254786
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098057
NCBI entrez gene - 571865     See in Manteia.
swissprot - E7F069
ZFIN ID - ZDB-GENE-120913-5
Ensembl - ENSDARG00000079972
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NFATC2ENSGALG00000007963Gallus gallus
 NFATC2ENSG00000101096Homo sapiens
 Nfatc2ENSMUSG00000027544Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfatc2a / nuclear factor of activated T cells 2a / NFATC2* / Q13469* / Q60591* / nuclear factor of activated T cells 2* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2*ENSDARG0000010092747
nfatc1 / nuclear factor of activated T cells 1 / O95644* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1*ENSDARG0000003616837
nfatc3a / nuclear factor of activated T cells 3a / Q12968* / NFATC3* / nuclear factor of activated T cells 3* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3*ENSDARG0000007629735
nfatc3b / nuclear factor of activated T cells 3bENSDARG0000005172932
nfatc4 / nuclear factor of activated T cells 4 / Q14934* / Q8K120* / Nuclear factor of activated T-cells, cytoplasmic 4 *ENSDARG0000005416229
nfat5a / nuclear factor of activated T cells 5a / NFAT5* / Q9WV30* / O94916* / nuclear factor of activated T cells 5*ENSDARG0000002087220
nfat5b / nuclear factor of activated T cells 5b / NFAT5* / Q9WV30* / O94916* / nuclear factor of activated T cells 5*ENSDARG0000010255620


Protein motifs (from Interpro)
Interpro ID Name
 IPR002909  IPT domain
 IPR008366  Nuclear factor of activated T cells (NFAT)
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011539  Rel homology domain (RHD), DNA-binding domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR015647  Nuclear factor of activated T-cells 1
 IPR032397  Rel homology dimerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Calcineurin activates NFAT
FCERI mediated Ca+2 mobilization
CLEC7A (Dectin-1) induces NFAT activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004988 ppp3ca / protein phosphatase 3, catalytic subunit, alpha isozyme / P63328* / Q08209* / protein phosphatase 3 catalytic subunit alpha* / protein phosphatase 3, catalytic subunit, alpha isoform*  / reaction / complex
 ENSDARG00000025106 ppp3cb / protein phosphatase 3, catalytic subunit, beta isozyme / Q08209* / P63328* / PPP3CA* / protein phosphatase 3 catalytic subunit alpha* / protein phosphatase 3, catalytic subunit, al...  / reaction / complex
 ENSDARG00000100825 calm2a / calm2b / calm3a / Q6PI52 / calmodulin 2a (phosphorylase kinase, delta)  / complex / reaction
 ENSDARG00000069360 ppp3r1b / protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b / PPP3R1* / P63098* / Q63810* / protein phosphatase 3 regulatory subunit B, alpha* / protein phosphata...  / complex / reaction






 

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