ENSDARG00000089766


Danio rerio

Features
Gene ID: ENSDARG00000089766
  
Biological name :nrg3b
  
Synonyms : neuregulin 3b / nrg3b
  
Possible biological names infered from orthology : neuregulin 3 / NRG3 / O35181 / P56975 / Pro-neuregulin-3, membrane-bound isoform Neuregulin-3
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 29350698
Gene end: 29624638
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106379
NCBI entrez gene - 101882495     See in Manteia.
swissprot - E7FCS5
ZFIN ID - ZDB-GENE-130603-38
Ensembl - ENSDARG00000089766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NRG3ENSGALG00000042812Gallus gallus
 NRG3ENSG00000185737Homo sapiens
 Nrg3ENSMUSG00000041014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nrg1 / neuregulin 1 / Q02297*ENSDARG0000010431413
nrg2b / neuregulin 2b / NRG2* / O14511* / neuregulin 2*ENSDARG0000008658511
nrg2a / neuregulin 2a / NRG2* / O14511* / neuregulin 2*ENSDARG0000007781810
CR749775.2ENSDARG000001171054


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002154  Neuregulin, C-terminal
 IPR013032  EGF-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0048513 animal organ development IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IBA


Pathways (from Reactome)
Pathway description
Signaling by ERBB2
Signaling by ERBB4
SHC1 events in ERBB2 signaling
PI3K events in ERBB4 signaling
SHC1 events in ERBB4 signaling
PIP3 activates AKT signaling
GRB2 events in ERBB2 signaling
PI3K events in ERBB2 signaling
RAF/MAP kinase cascade
ERBB2 Regulates Cell Motility
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
ERBB2 Activates PTK6 Signaling
Downregulation of ERBB2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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