ENSDARG00000089981


Danio rerio

Features
Gene ID: ENSDARG00000089981
  
Biological name :rnf146
  
Synonyms : ring finger protein 146 / rnf146
  
Possible biological names infered from orthology : Q9CZW6 / Q9NTX7
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 40525985
Gene end: 40536089
  
Corresponding Affymetrix probe sets: Dr.12666.1.S1_at (Zebrafish Array)   Dr.12666.1.S1_x_at (Zebrafish Array)   Dr.16536.1.A1_s_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128360
Ensembl peptide - ENSDARP00000112974
Ensembl peptide - ENSDARP00000121982
NCBI entrez gene - 334065     See in Manteia.
swissprot - F1R5P0
swissprot - H9KUX0
ZFIN ID - ZDB-GENE-030131-5997
Ensembl - ENSDARG00000089981
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNF146ENSGALG00000026820Gallus gallus
 Q9NTX7ENSG00000118518Homo sapiens
 Q9CZW6ENSMUSG00000038876Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004170  WWE domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018123  WWE domain, subgroup
 IPR033509  E3 ubiquitin-protein ligase RNF146


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016567 protein ubiquitination IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:0072572 poly-ADP-D-ribose binding IEA


Pathways (from Reactome)
Pathway description
TCF dependent signaling in response to WNT
Degradation of AXIN
Ub-specific processing proteases
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000062897 tnksb / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b / TNKS* / Q6PFX9* / O95271* / tankyrase* / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase*  / complex / reaction
 ENSDARG00000077650 tnksa / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a / TNKS* / Q6PFX9* / O95271* / tankyrase* / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase*  / complex / reaction
 ENSDARG00000102964 axin1 / O15169*  / complex / reaction
 ENSDARG00000100149 axin2 / P57095 / axin 2 (conductin, axil) / O88566* / Q9Y2T1*  / complex / reaction






 

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