ENSDARG00000090654


Danio rerio

Features
Gene ID: ENSDARG00000090654
  
Biological name :gak
  
Synonyms : cyclin G associated kinase / gak
  
Possible biological names infered from orthology : cyclin-G-associated kinase isoform 3 / O14976
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 9441198
Gene end: 9540770
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000111020
Ensembl peptide - ENSDARP00000141649
NCBI entrez gene - 100151158     See in Manteia.
swissprot - A0A0R4IWM3
swissprot - F1QH49
ZFIN ID - ZDB-GENE-041210-358
Ensembl - ENSDARG00000090654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GAKENSGALG00000015352Gallus gallus
 GAKENSG00000178950Homo sapiens
 GakENSMUSG00000062234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnajc6 / DnaJ (Hsp40) homolog, subfamily C, member 6 / O75061* / Q80TZ3* / DnaJ heat shock protein family (Hsp40) member C6*ENSDARG0000007989129
tns1a / tensin 1a / TNS1* / Q9HBL0* / tensin 1*ENSDARG0000007884215
tns2a / tensin 2a / TNS2* / Q63HR2* / Q8CGB6* / tensin 2* / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA.*ENSDARG0000007629214
tns1b / tensin 1b / TNS1* / Q9HBL0* / tensin 1*ENSDARG0000002084514
tns2b / tensin 2b / TNS2* / Q63HR2* / Q8CGB6* / tensin 2* / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA.*ENSDARG0000006839711
tpte / transmembrane phosphatase with tensin homology / TPTE2* / Q6XPS3* / P56180* / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2*ENSDARG000000569858
ptena / phosphatase and tensin homolog A / PTEN* / O08586* / P60484* / phosphatase and tensin homolog*ENSDARG000000710187
ptenb / phosphatase and tensin homolog B / PTEN* / O08586* / P60484* / phosphatase and tensin homolog*ENSDARG000000566236
tns3.1 / tensin 3, tandem duplicate 1ENSDARG000000956546
tns3.2 / tensin 3, tandem duplicate 2 / TNS3* / Q5SSZ5* / Q68CZ2* / tensin 3*ENSDARG000000319114


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000719  Protein kinase domain
 IPR001623  DnaJ domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR014020  Tensin phosphatase, C2 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029023  Tensin-type phosphatase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006898 receptor-mediated endocytosis IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0031982 vesicle IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain degenerate , abnormal
brain cell degenerate , abnormal
Show

 ZFA:0000029 hindbrain hindbrain increased size , abnormal
Show

 ZFA:0000106 extension extension decreased thickness , abnormal
Show

 ZFA:0000107 eye eye cell degenerate , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr