ENSDARG00000056985


Danio rerio

Features
Gene ID: ENSDARG00000056985
  
Biological name :tpte
  
Synonyms : tpte / transmembrane phosphatase with tensin homology
  
Possible biological names infered from orthology : P56180 / Q6XPS3 / TPTE2 / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 24690534
Gene end: 24707956
  
Corresponding Affymetrix probe sets: Dr.7278.1.A1_at (Zebrafish Array)   Dr.7278.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000074004
Ensembl peptide - ENSDARP00000157510
NCBI entrez gene - 327292     See in Manteia.
swissprot - F1QG29
ZFIN ID - ZDB-GENE-030131-5503
Ensembl - ENSDARG00000056985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000017031Gallus gallus
 TPTEENSG00000274391Homo sapiens
 TPTE2ENSG00000132958Homo sapiens
 TpteENSMUSG00000031481Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptena / phosphatase and tensin homolog A / PTEN* / O08586* / P60484* / phosphatase and tensin homolog*ENSDARG0000007101824
ptenb / phosphatase and tensin homolog B / PTEN* / O08586* / P60484* / phosphatase and tensin homolog*ENSDARG0000005662323
tns1b / tensin 1b / TNS1* / Q9HBL0* / tensin 1*ENSDARG0000002084520
gak / cyclin G associated kinase / O14976* / cyclin-G-associated kinase isoform 3 *ENSDARG0000009065420
tns1a / tensin 1a / TNS1* / Q9HBL0* / tensin 1*ENSDARG0000007884218
tns2a / tensin 2a / TNS2* / Q63HR2* / Q8CGB6* / tensin 2* / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA.*ENSDARG0000007629217
tns2b / tensin 2b / TNS2* / Q63HR2* / Q8CGB6* / tensin 2* / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA.*ENSDARG0000006839716
dnajc6 / DnaJ (Hsp40) homolog, subfamily C, member 6 / O75061* / Q80TZ3* / DnaJ heat shock protein family (Hsp40) member C6*ENSDARG0000007989115
tns3.1 / tensin 3, tandem duplicate 1ENSDARG0000009565413
tns3.2 / tensin 3, tandem duplicate 2 / TNS3* / Q5SSZ5* / Q68CZ2* / tensin 3*ENSDARG000000319113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR005821  Ion transport domain
 IPR014020  Tensin phosphatase, C2 domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029023  Tensin-type phosphatase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IDA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005216 ion channel activity IDA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the Golgi membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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