ENSMUSG00000031481


Mus musculus

Features
Gene ID: ENSMUSG00000031481
  
Biological name :Tpte
  
Synonyms : Tpte / transmembrane phosphatase with tensin homology
  
Possible biological names infered from orthology : P56180 / Q6XPS3 / TPTE2 / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A2
Gene start: 22283441
Gene end: 22371418
  
Corresponding Affymetrix probe sets: 10570794 (MoGene1.0st)   1427690_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147872
Ensembl peptide - ENSMUSP00000076435
Ensembl peptide - ENSMUSP00000147781
NCBI entrez gene - 234129     See in Manteia.
MGI - MGI:2446460
RefSeq - XM_017312675
RefSeq - NM_199257
RefSeq - XM_017312674
RefSeq Peptide - NP_954866
swissprot - A0A1B0GS38
swissprot - G5E8H5
swissprot - A0A1B0GSB8
Ensembl - ENSMUSG00000031481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpteENSDARG00000056985Danio rerio
 ENSGALG00000017031Gallus gallus
 TPTEENSG00000274391Homo sapiens
 TPTE2ENSG00000132958Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pten / O08586 / phosphatase and tensin homolog / P60484*ENSMUSG0000001366319
Gak / cyclin-G-associated kinase isoform 3 / O14976* / cyclin G associated kinase*ENSMUSG0000006223417
Tns1 / tensin 1 / Q9HBL0*ENSMUSG0000005532216
Tns2 / Q8CGB6 / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA. / Q63HR2* / tensin 2*ENSMUSG0000003700314
Dnajc6 / Q80TZ3 / DnaJ heat shock protein family (Hsp40) member C6 / O75061*ENSMUSG0000002852814
Tns3 / Q5SSZ5 / Tensin-3 / Q68CZ2*ENSMUSG0000002042212
Tns4 / Q8BZ33 / Tensin-4 / Q8IZW8*ENSMUSG000000176072


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR014020  Tensin phosphatase, C2 domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029023  Tensin-type phosphatase domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005794 Golgi apparatus ISA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the Golgi membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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