ENSMUSG00000017607


Mus musculus

Features
Gene ID: ENSMUSG00000017607
  
Biological name :Tns4
  
Synonyms : Q8BZ33 / Tensin-4 / Tns4
  
Possible biological names infered from orthology : Q8IZW8
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 99065678
Gene end: 99089306
  
Corresponding Affymetrix probe sets: 10390748 (MoGene1.0st)   1439347_at (Mouse Genome 430 2.0 Array)   1444254_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017751
NCBI entrez gene - 217169     See in Manteia.
MGI - MGI:2144377
RefSeq - NM_172564
RefSeq Peptide - NP_766152
swissprot - Q8BZ33
Ensembl - ENSMUSG00000017607
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNS4ENSGALG00000028308Gallus gallus
 TNS4ENSG00000131746Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tns3 / Q5SSZ5 / Tensin-3 / Q68CZ2*ENSMUSG0000002042234
Tns1 / tensin 1 / Q9HBL0*ENSMUSG0000005532234
Tns2 / Q8CGB6 / Mus musculus tensin 2 (Tns2), transcript variant 2, mRNA. / Q63HR2* / tensin 2*ENSMUSG0000003700331
Gak / cyclin-G-associated kinase isoform 3 / O14976* / cyclin G associated kinase*ENSMUSG0000006223411
Dnajc6 / Q80TZ3 / DnaJ heat shock protein family (Hsp40) member C6 / O75061*ENSMUSG0000002852811
Pten / O08586 / phosphatase and tensin homolog / P60484*ENSMUSG000000136635
Tpte / transmembrane phosphatase with tensin homology / TPTE2* / Q6XPS3* / P56180* / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2*ENSMUSG000000314812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR033929  Tensin, phosphotyrosine-binding domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008104 protein localization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
MET interacts with TNS proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028864 Hgf / Q08048 / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain / P14210* / hepatocyte growth factor*  / reaction / complex
 ENSMUSG00000009376 Met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction / complex
 ENSMUSG00000025809 Itgb1 / P09055 / Integrin beta-1 / P05556* / integrin subunit beta 1*  / complex






 

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