ENSDARG00000091187


Danio rerio

Features
Gene ID: ENSDARG00000091187
  
Biological name :BX649250.1
  
Synonyms : BX649250.1
  
Possible biological names infered from orthology : Q96RL1 / ubiquitin interaction motif containing 1 / UIMC1
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 37049427
Gene end: 37075542
  
Corresponding Affymetrix probe sets: Dr.16383.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107825
swissprot - E7F5D0
Ensembl - ENSDARG00000091187
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UIMC1ENSGALG00000001158Gallus gallus
 UIMC1ENSG00000087206Homo sapiens
 Uimc1ENSMUSG00000025878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006302 double-strand break repair IBA
 biological_processGO:0045739 positive regulation of DNA repair IBA
 biological_processGO:0070537 histone H2A K63-linked deubiquitination IBA
 cellular_componentGO:0070531 BRCA1-A complex IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IBA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002385 atm / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction / complex
 ENSDARG00000026225 nsd2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *  / complex / reaction
 ENSDARG00000008748 ube2na / ubiquitin-conjugating enzyme E2Na / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction / complex
 ENSDARG00000028198 Q6PEH5 / ube2v2 / ubiquitin-conjugating enzyme E2 variant 2 / Q15819* / ubiquitin conjugating enzyme E2 V2*  / reaction / complex
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000045877 ube2nb / ubiquitin-conjugating enzyme E2Nb / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction / complex
 ENSDARG00000040303 nbn / nibrin / Q5I2W8 / O60934* / Q9R207*  / reaction / complex
 ENSDARG00000043339 Q1LVP6 / abraxas2a / abraxas 2a, BRISC complex subunit / Q8BPZ8* / Q6UWZ7* / ABRAXAS1* / BRCA1 A complex subunit* / abraxas 1, BRCA1 A complex subunit*  / reaction / complex
 ENSDARG00000044949 rnf8 / ring finger protein 8, E3 ubiquitin protein ligase / Q8VC56* / O76064* / Gm28043* / ring finger protein 8* / E3 ubiquitin-protein ligase RNF8 *  / reaction / complex
 ENSDARG00000073841 herc2 / HECT and RLD domain containing E3 ubiquitin protein ligase 2 / O95714* / Q4U2R1* / E3 ubiquitin-protein ligase HERC2 *  / reaction / complex
 ENSDARG00000086764 mdc1 / mediator of DNA damage checkpoint 1 / Q14676*  / complex / reaction
 ENSDARG00000038917 rad50 / RAD50 homolog, double strand break repair protein / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / reaction / complex
 ENSDARG00000042215 pias4b / protein inhibitor of activated STAT, 4b / PIAS4* / Q9JM05* / Q8N2W9* / protein inhibitor of activated STAT 4*  / reaction / complex
 ENSDARG00000105014 mre11a / MRE11 homolog A, double strand break repair nuclease / MRE11* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex / reaction
 ENSDARG00000112483 rnf168 / ring finger protein 168 / Q8IYW5*  / complex / reaction






 

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