ENSDARG00000098226


Danio rerio

Features
Gene ID: ENSDARG00000098226
  
Biological name :smpd3
  
Synonyms : smpd3 / sphingomyelin phosphodiesterase 3, neutral
  
Possible biological names infered from orthology : Q9JJY3 / Q9NY59 / sphingomyelin phosphodiesterase 3
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 13068019
Gene end: 13105310
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133737
NCBI entrez gene - 568381     See in Manteia.
RefSeq - NM_001122750
RefSeq Peptide - NP_001116222
swissprot - B1B5D9
ZFIN ID - ZDB-GENE-081104-280
Ensembl - ENSDARG00000098226
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMPD3ENSGALG00000034950Gallus gallus
 SMPD3ENSG00000103056Homo sapiens
 Smpd3ENSMUSG00000031906Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smpd5 / F1QG30 / sphingomyelin phosphodiesterase 5ENSDARG0000005981134


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0061300 cerebellum vasculature development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
TNFR1-mediated ceramide production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001267 cranial vasculature cranial vasculature hemorrhagic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018569 tnfrsf1a / tumor necrosis factor receptor superfamily, member 1a / P19438* / P25118* / TNF receptor superfamily member 1A*  / reaction / complex
 ENSDARG00000013598 tnfb / tumor necrosis factor b (TNF superfamily, member 2) / LTA* / TNF* / P01375* / P06804* / P09225* / P01374* / lymphotoxin A* / lymphotoxin alpha* / tumor necrosis factor*  / reaction / complex
 ENSDARG00000051920 nsmaf / neutral sphingomyelinase (N-SMase) activation associated factor / Q92636* / neutral sphingomyelinase activation associated factor*  / reaction / complex
 ENSDARG00000041619 rack1 / O42248 / receptor for activated C kinase 1 / P68040* / P63244* / Receptor of activated protein C kinase 1 Receptor of activated protein C kinase 1, N-terminally processed*  / reaction / complex






 

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