MP:0000060 | delayed bone ossification | "late onset of the formation of bone" [J:40203] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
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MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
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MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
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MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
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MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
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MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
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MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001183 | overexpanded alveoli | "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
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MP:0001255 | decreased body height | "decreased shoulder to floor distance compared to controls" [dlb:Donna Burkart, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
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MP:0001547 | abnormal lipid level | "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
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MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
|
MP:0001938 | delayed sexual maturation | "immaturity of the sexual organs at a given age" [J:61190] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0001958 | emphysema | "lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33629] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
|
MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
|
MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac
|
MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0002270 | abnormal alveoli morphology | "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
|
MP:0002427 | dwarfism | "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0002904 | increased circulating parathyroid hormone level | "greater than expected blood concentration of this regulator of calcium and phosphorous concentration" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0003409 | decreased width of hypertrophic chondrocyte zone | "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0003582 | abnormal ovary development | "abnormal morphogenesis of the female reproductive gland containing the germ cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0003830 | abnormal testis development | "abnormal morphogenesis of the male reproductive gland containing the germ cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:100020] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0004163 | abnormal adenophysis morphology | "any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0004189 | abnormal alveolar process | "any structural anomaly of the thickened ridge of bone in the mandible and maxilla that holds the tooth sockets" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004201 | fetal growth retardation | "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004358 | bowed tibia | "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004361 | bowed ulna | "increased curvature of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004373 | bowed humerus | "increased curvature of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004374 | bowed radius | "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004506 | abnormal pubic bone morphology | "any structural anomaly in the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004507 | abnormal ischium morphology | "any structural anomaly of the lowest of the three major bones that constitute each half of the pelvis, distinct at birth but later becoming fused with the ilium and pubis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004675 | rib fractures | "a crack or break in the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0004701 | decreased circulating insulin-like growth factor I level | "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0004986 | abnormal osteoblast morphology | "any structural anomaly of a bone-forming cell, which normally forms an osseous matrix (osteoid) in which it becomes enclosed as an osteocyte" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0005298 | abnormal clavicle morphology | "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0005471 | decreased thyroxine level | "less than the normal concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:13923] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0005473 | decreased triiodothyronine level | "less than the normal concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0006322 | abnormal perichondrium morphology | "any structural anomaly of the fibrous connective tissue that surrounds all non-joint end cartilage" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", J:117033, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0008277 | abnormal sternum ossification | "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0008329 | decreased somatotroph cell number | "reduced number of an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin" [CL:0000295, MESH:A06.407.747.608.937] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0008335 | decreased gonadotroph cell number | "reduced number of the anterior pituitary cells that can produce both follicle stimulating hormone (FSH) and luteinizing hormone (LH)" [MESH:A06.407.747.608.750] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0008338 | decreased thyrotroph cell number | "reduced number of an anterior pituitary cell that produces thyroid-stimulating hormone" [MESH:A06.407.747.608.968] |
Show
Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0008341 | decreased corticotroph cell number | "reduced number of an anterior pituitary basophilic cell that produces adrenocorticotrophic hormone (ACTH)" [CL:0000467, MESH:A06.407.747.608.500] |
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Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0010869 | decreased bone trabecula number | "decreased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [http://www.dorlands.com/ "Dorland s Illustrated Medical Dictionary, 31st edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0010895 | increased lung compliance | "increased ability of the lung to distend in response to pressure without disruption, usually expressed as the unit volume of change in the lung per unit of pressure" [ISBN:070202788 "Saunders Comprehensive Veterinary Dictionary, 3rd edition"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
|
MP:0010971 | abnormal periosteum morphology | "any structural anomaly of the thick fibrous membrane that closely invests the entire surface of a bone except the articular cartilage at synovial joints" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|
MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: involves: C3H/HeN * C57BL/6N
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: B6N.Cg-Smpd3fro
Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: C3H.Cg-Smpd3fro
|
MP:0013340 | abnormal pituicyte morphology | "any structural anomaly of the distinctive fusiform cells present in the pars nervosa of the posterior pituitary gland which resemble astrocytes/glial cells of the CNS and assist in the storage and release of neurohypophysial hormones" [MGI:Anna] |
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Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0014162 | decreased circulating cortisol level | "less than the normal blood concentration of the principal glucocorticoid produced by the zona fasciculata of the adrenal cortex within the adrenal gland and released in response to stress and a low level of blood glucose" [https://en.wikipedia.org/wiki/Cortisol] |
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Allelic Composition: Sh2d1atm1Lyin/Sh2d1atm1Lyin Genetic Background: involves: 129S2/SvPas * C57BL/6
|
MP:0030542 | abnormal dentin development | "any anomaly in the process whose specific outcome is the formation of dentin, the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root; dentinogenesis begins prior to enamel formation and is initiated by the odontoblasts of the dental pulp; dentin is derived from the dental papilla of the tooth germ; after apposition of predentin and maturation into dentin, the cell bodies of the odontoblasts remain in the pulp inside the tooth, along its outer wall; unlike enamel, dentin continues to form throughout life and can be initiated in response to stimuli, such as tooth decay or attrition" [GO:0097187, https://en.wikipedia.org/wiki/Dentin] |
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Allelic Composition: Smpd3fro/Smpd3fro Genetic Background: Not Specified
|