ENSDARG00000098257


Danio rerio

Features
Gene ID: ENSDARG00000098257
  
Biological name :pcdh15a
  
Synonyms : pcdh15a / protocadherin-related 15a
  
Possible biological names infered from orthology : PCDH15 / Protocadherin-15 / protocadherin related 15 / Q96QU1 / Q99PJ1
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 41125358
Gene end: 41546779
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130788
Ensembl peptide - ENSDARP00000149410
Ensembl peptide - ENSDARP00000135210
NCBI entrez gene - 368476     See in Manteia.
RefSeq - NM_001012482
RefSeq Peptide - NP_001012500
swissprot - A0A1V0D7A1
swissprot - A0A0R4ILG0
swissprot - Q5ICW6
ZFIN ID - ZDB-GENE-030616-3
Ensembl - ENSDARG00000098257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCDH15ENSGALG00000002744Gallus gallus
 PCDH15ENSG00000150275Homo sapiens
 Pcdh15ENSMUSG00000052613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pcdh15b / protocadherin-related 15b / Q99PJ1* / PCDH15* / Q96QU1* / Protocadherin-15 * / protocadherin related 15*ENSDARG0000000812765
pcdh11 / protocadherin 11 / Q9BZA7* / Q9BZA8* / PCDH11Y* / PCDH11X* / protocadherin 11 X-linked* / protocadherin 11 Y-linked*ENSDARG0000009865213
pcdh9 / protocadherin 9 / Q9HC56*ENSDARG0000006326413
pcdh7a / protocadherin 7aENSDARG0000007889813
pcdh7b / protocadherin 7b / PCDH7* / O60245* / protocadherin 7*ENSDARG0000006061013
pcdh1a / protocadherin 1a / PCDH1* / Q08174* / protocadherin 1*ENSDARG0000006272013
pcdh2aa15 / protocadherin 2 alpha a 15 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* ...ENSDARG0000008813612
pcdh1b / protocadherin 1b / PCDH1* / Q08174* / protocadherin 1*ENSDARG0000003617512
pcdh1a3 / protocadherin 1 alpha 3 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / Q9Y...ENSDARG0000010360211
BX957322.3ENSDARG0000010735311
pcdh2aa1 / protocadherin 2 alpha a 1 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / ...ENSDARG0000003769511
pcdh1a3 / pcdh1a6 / protocadherin 1 alpha 3 / PCDHA3* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y...ENSDARG0000010459811
pcdh2ab2 / protocadherin 2 alpha b2 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / Q...ENSDARG0000003769111
pcdh10b / protocadherin 10bENSDARG0000010282411
pcdh20 / protocadherin 20 / Q8N6Y1* / AL592490.1*ENSDARG0000003642411
pcdh2ab12 / protocadherin 2 alpha b 12 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* ...ENSDARG0000010408011
pcdh1g9 / protocadherin 1 gamma 9 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / Q9Y...ENSDARG0000005751911
pcdh2ab2 / protocadherin 2 alpha b2 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / Q...ENSDARG0000009946811
pcdh2ab3 / protocadherin 2 alpha b 3 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / ...ENSDARG0000010271911
pcdh2ab1 / protocadherin 2 alpha b 1 / PCDHA4* / O88689* / PCDHA1* / PCDHA9* / Q91Y11* / Q91Y13* / Q91Y20* / Q9UN72* / Q9UN73* / Q9UN74* / Q9UN75* / Q9Y5H5* / Q9Y5H6* / Q9Y5H7* / Q9Y5H8* / ...ENSDARG0000007190411


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007423 sensory organ development IMP
 biological_processGO:0035315 hair cell differentiation IMP
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IGI
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000217 inner ear inner ear quality , abnormal
inner ear morphology , abnormal
inner ear stereocilium bundle disorganized , abnormal
inner ear stereocilium bundle splayed , abnormal
Show

 ZFA:0001094 whole organism whole organism unbalanced , abnormal
whole organism decreased behavioural activity , abnormal
whole organism circling , abnormal
whole organism decreased amount , abnormal
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 ZFA:0009366 hair cell hair cell quality , abnormal
hair cell morphology , abnormal
hair cell stereocilium bundle direction , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell endocytosis decreased process quality , abnormal
neuromast hair cell stereocilium bundle decreased amount , abnormal
neuromast hair cell cuticular plate mislocalised , abnormal
neuromast hair cell intraciliary transport decreased process quality , abnormal
neuromast hair cell kinocilium absent , abnormal
neuromast hair cell kinocilium decreased length , abnormal
neuromast hair cell kinocilium decreased amount , abnormal
neuromast hair cell cilium assembly decreased process quality , abnormal
neuromast hair cell kinociliary basal body spatial pattern , abnormal
neuromast hair cell decreased functionality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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