ENSDARG00000100494


Danio rerio

Features
Gene ID: ENSDARG00000100494
  
Biological name :pbx1a
  
Synonyms : pbx1a / pre-B-cell leukemia homeobox 1a
  
Possible biological names infered from orthology : P40424 / P41778 / PBX1 / PBX homeobox 1 / Pre-B-cell leukemia transcription factor 1
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 18698388
Gene end: 18830794
  
Corresponding Affymetrix probe sets: Dr.21042.1.S1_at (Zebrafish Array)   Dr.21071.1.S1_s_at (Zebrafish Array)   Dr.8172.1.S1_at (Zebrafish Array)   NM_131615_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136221
Ensembl peptide - ENSDARP00000138945
NCBI entrez gene - 58138     See in Manteia.
RefSeq - NM_131615
RefSeq Peptide - NP_571690
swissprot - Q9I9B6
swissprot - Q9I9B7
ZFIN ID - ZDB-GENE-000405-1
Ensembl - ENSDARG00000100494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PBX1ENSGALG00000003429Gallus gallus
 PBX1ENSG00000185630Homo sapiens
 Pbx1ENSMUSG00000052534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pbx1b / pre-B-cell leukemia homeobox 1b / PBX1* / P40424* / PBX homeobox 1*ENSDARG0000010113194
pbx3a / pre-B-cell leukemia homeobox 3a / PBX3* / P40426* / O35317* / PBX homeobox 3* / Pre-B-cell leukemia transcription factor 3 *ENSDARG0000008926274
pbx3b / pre-B-cell leukemia homeobox 3b / PBX3* / P40426* / O35317* / PBX homeobox 3* / Pre-B-cell leukemia transcription factor 3 *ENSDARG0000001361565
pbx4 / pre-B-cell leukemia transcription factor 4 / Q99NE9* / Q9BYU1* / PBX homeobox 4* / Mus musculus pre B cell leukemia homeobox 4 (Pbx4), transcript variant 4, mRNA.*ENSDARG0000005215063
pbx2 / pre-B-cell leukemia homeobox 2 / O35984* / P40425* / PBX homeobox 2*ENSDARG0000001971763


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR005542  PBX
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0048795 swim bladder morphogenesis IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder physical object quality , abnormal
swim bladder morphology , abnormal
Show

 ZFA:0000094 blood island blood island neutrophil decreased amount , abnormal
Show

 ZFA:0000254 pancreas primordium pancreas primordium physical object quality , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch physical object quality , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr