ENSDARG00000100990


Danio rerio

Features
Gene ID: ENSDARG00000100990
  
Biological name :nme3
  
Synonyms : nme3 / NME/NM23 nucleoside diphosphate kinase 3
  
Possible biological names infered from orthology : Nucleoside diphosphate kinase 3 / Q13232 / Q9WV85
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 15990547
Gene end: 16000168
  
Corresponding Affymetrix probe sets: Dr.1125.1.S1_at (Zebrafish Array)   NM_130928_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000139313
Ensembl peptide - ENSDARP00000132457
NCBI entrez gene - 30085     See in Manteia.
RefSeq - NM_130928
RefSeq - XM_021469289
RefSeq Peptide - NP_571003
swissprot - Q9PTF3
swissprot - A0A0R4IS05
ZFIN ID - ZDB-GENE-000210-34
Ensembl - ENSDARG00000100990
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NME3ENSGALG00000027635Gallus gallus
 NME3ENSG00000103024Homo sapiens
 Nme3ENSMUSG00000073435Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...ENSDARG0000010379163
nme2a / NME/NM23 nucleoside diphosphate kinase 2a / NME2* / NME1* / Q01768* / P15531* / P15532* / P22392* / Gm20390* / NME1-NME2* / NME1-NME2 readthrough* / Nucleoside diphosphate kinase A ...ENSDARG0000004382060
nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...ENSDARG0000009942059
nme4 / NME/NM23 nucleoside diphosphate kinase 4 / O00746* / Q9WV84* / Nucleoside diphosphate kinase, mitochondrial *ENSDARG0000008839055
nme7 / NME/NM23 family member 7 / Q9Y5B8*ENSDARG0000005619328
nme8 / NME/NM23 family member 8 / NME9* / Q86XW9* / NME/NM23 family member 9*ENSDARG0000009894427
nme6 / Q6DI51 / NME/NM23 nucleoside diphosphate kinase 6 / O75414* / O88425* / Nucleoside diphosphate kinase 6 *ENSDARG0000001613826
nme5 / NME/NM23 family member 5 / P56597* / Q99MH5* / Nucleoside diphosphate kinase homolog 5 *ENSDARG0000004161724


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IEA
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0106071 positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle heart contraction process quality , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism 3,5-cyclic AMP decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043820 nme2a / NME/NM23 nucleoside diphosphate kinase 2a / NME2* / NME1* / Q01768* / P15531* / P15532* / P22392* / Gm20390* / NME1-NME2* / NME1-NME2 readthrough* / Nucleoside diphosphate kinase A ...  / complex
 ENSDARG00000100990 nme3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232* / Q9WV85* / Nucleoside diphosphate kinase 3 *  / complex
 ENSDARG00000103791 nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex
 ENSDARG00000099420 nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr