ENSMUSG00000073435


Mus musculus

Features
Gene ID: ENSMUSG00000073435
  
Biological name :Nme3
  
Synonyms : Nme3 / Nucleoside diphosphate kinase 3 / Q9WV85
  
Possible biological names infered from orthology : NME/NM23 nucleoside diphosphate kinase 3 / Q13232
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 24896500
Gene end: 24897522
  
Corresponding Affymetrix probe sets: 10442643 (MoGene1.0st)   1448905_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024978
NCBI entrez gene - 79059     See in Manteia.
MGI - MGI:1930182
RefSeq - NM_019730
RefSeq Peptide - NP_062704
swissprot - Q9WV85
Ensembl - ENSMUSG00000073435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nme3ENSDARG00000100990Danio rerio
 NME3ENSGALG00000027635Gallus gallus
 NME3ENSG00000103024Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nme1 / P15532 / Nucleoside diphosphate kinase A / P15531* / NME/NM23 nucleoside diphosphate kinase 1*ENSMUSG0000003760157
Nme2 / Q01768 / NME/NM23 nucleoside diphosphate kinase 2 / P22392* / NME1-NME2* / NME1-NME2 readthrough*ENSMUSG0000002085757
Gm20390 / NME2* / P22392* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*ENSMUSG0000009122856
Nme4 / Q9WV84 / Nucleoside diphosphate kinase, mitochondrial / O00746* / NME/NM23 nucleoside diphosphate kinase 4*ENSMUSG0000002417756
Nme6 / O88425 / Nucleoside diphosphate kinase 6 / O75414* / NME/NM23 nucleoside diphosphate kinase 6*ENSMUSG0000003247827
Nme5 / Q99MH5 / Nucleoside diphosphate kinase homolog 5 / P56597* / NME/NM23 family member 5*ENSMUSG0000003598425
Nme7 / NME/NM23 family member 7 / Q9Y5B8*ENSMUSG0000002657524
Nme8 / Q715T0 / Thioredoxin domain-containing protein 3 / Q8N427* / NME/NM23 family member 8*ENSMUSG0000004113820
Nme9 / NME/NM23 family member 9 / Q86XW9*ENSMUSG0000004624212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain
 IPR036850  Nucleoside diphosphate kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IEA
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Irf5tm1Ttg/Irf5tm1Ttg
Genetic Background: B6.129P2-Irf5tm1Ttg

Allelic Composition: Nme3tm1Bgh/Nme3+,th49/t+
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037601 Nme1 / P15532 / Nucleoside diphosphate kinase A / P15531* / NME/NM23 nucleoside diphosphate kinase 1*  / complex
 ENSMUSG00000073435 Nme3 / Q9WV85 / Nucleoside diphosphate kinase 3 / Q13232* / NME/NM23 nucleoside diphosphate kinase 3*  / complex






 

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