ENSG00000103024


Homo sapiens

Features
Gene ID: ENSG00000103024
  
Biological name :NME3
  
Synonyms : NME3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 1770286
Gene end: 1771730
  
Corresponding Affymetrix probe sets: 204862_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454498
Ensembl peptide - ENSP00000455435
Ensembl peptide - ENSP00000456160
Ensembl peptide - ENSP00000219302
Ensembl peptide - ENSP00000455271
NCBI entrez gene - 4832     See in Manteia.
OMIM - 601817
RefSeq - XM_011522504
RefSeq - NM_002513
RefSeq - XM_005255332
RefSeq - XM_011522503
RefSeq Peptide - NP_002504
swissprot - H3BMQ7
swissprot - Q13232
swissprot - H3BPD9
swissprot - H3BPR2
swissprot - H3BRA8
Ensembl - ENSG00000103024
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nme3ENSDARG00000100990Danio rerio
 NME3ENSGALG00000027635Gallus gallus
 Nme3ENSMUSG00000073435Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NME1 / P15531 / NME/NM23 nucleoside diphosphate kinase 1ENSG0000023967261
NME1-NME2 / NME1-NME2 readthroughENSG0000001105259
NME2 / P22392 / NME/NM23 nucleoside diphosphate kinase 2ENSG0000024367859
NME4 / O00746 / NME/NM23 nucleoside diphosphate kinase 4ENSG0000010320253
NME6 / O75414 / NME/NM23 nucleoside diphosphate kinase 6ENSG0000017211329
NME5 / P56597 / NME/NM23 family member 5ENSG0000011298125
NME8 / Q8N427 / NME/NM23 family member 8ENSG0000008628824
NME7 / Q9Y5B8 / NME/NM23 family member 7ENSG0000014315621
NME9 / Q86XW9 / NME/NM23 family member 9ENSG0000018132212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain
 IPR036850  Nucleoside diphosphate kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IEA
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0015949 nucleobase-containing small molecule interconversion TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103024 NME3 / Q13232 / NME/NM23 nucleoside diphosphate kinase 3  / complex
 ENSG00000239672 NME1 / P15531 / NME/NM23 nucleoside diphosphate kinase 1  / complex






 

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